Lump In Neck

Question 1

Differentials

Answer 1

Lymphoma
Reactivate lymphadenopathy 
Thyroid swelling
Thyroglossal cyst
Pharyngeal pouch
Cystic hygroma
Branchial cyst
Cervical rib
Carotid aneurysm 
Laryngeal cancer

Question 2

Investigations

Answer 2

US
LN palpation
Thyroid function test and palpation
Examine cranial nerves
FBC, inflammatory markers, blood cultures
CXR, biopsy, LFTs - malignancy?
Barium swallow - pharyngeal pouch
Contrast CT neck - branchial cyst (drain = acellular)
Stick tongue out - thyroglossal cyst moves up