Luminal Pathology (Esophagus, Stomach, and, Intestine)

Question 1

Herpes vs CMV on histology

Answer 1

Herpes infects squamous cells and multinuclear inclusions

CMV infects below squamous cells and has “owl eye inclusions”

Question 2

Type A vs B chronic gastritis

Answer 2

Type A = autoimmune gastritis

Type B = H. Pylori

Question 3

Autoimmune Gastritis: pathogenesis, distribution, complications

Answer 3

Autoantibodies to parietal cells, leads to pernicious anemia because Ab to IF decreases B12 absorbtion

Affects body of stomach (spares antrum),

Megaloblastic anemia, gastric adenocarcinoma and carcinoid tumors

Question 4

H. Pylori induced chronic gastritis: pathogenesis, distribution, complications

Answer 4

Attacks foveolar cells (mucous neck cells)

Affects antrum of stomach

Small, curved gram - rods

Duodenal and gastric ulcers, risk of MALT lymphoma, risk of gastric adenocarcinoma and B cell lymphoma