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MAD > LPI > Flashcards

LPI Flashcards

1
Q

VIRULENCIAS DO STAPHYLOCOCCUS AUREUS

A

CAPSULA - EVASINA
BIOFILME - EVASINA
MSCRAMM - EVASINA
ACIDO TEICOICO - ADESINA
PROTEÍNA A - EVASINA E ADESINA
COAGULASE - ENZIMA
MSCRAMM - ADESINA

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2
Q

CAPSULA

A

PROTEGE CONTRA FAGOCITOSE - ADESINA

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3
Q

ACIDO TEICOICO

A

ATIVA SISTEMA COMPLEMENTO VIA ALTERNATIVA - ADESINA

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4
Q

PROTEINA A

A

ADESINA LIGANDO A PORCAO FC DO ANTICORPO (IG)

VIRA EVASINA IMPEDINDO/MASCARANDO O RECONHECIMENTO E FAGOCITOSE

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5
Q

MSCRAMM

A

PROTEINA QUE COLA NA MATRIZ CELULAR (SE LIGA AO FIBRINONECTINA E COLAGENO) - ADESINAS

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6
Q

BIOFILME

A

PIA - ADESINA INTRACELULAR POLISSACARIDEA
PELICULA - EVASION

ESTRUTURA ADESINA
FUNCAO EVASINA

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7
Q

COAGULASE

A

ENZIMA QUE COAGULA O PLASMA, DNASE, HIALURONIDASE, LIPASE, CATALASE

PODE CAUSAR SEPSE

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8
Q

PARA QUE A INFECCAO SEJA CAUSADA

A

OS FATORES DE VIRULENCIA ATUEM DE FORMA CORDENADA, REDUNDANTE PARA UM DOS FATORES FUNCIONAR SE CASO UM FALHE

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9
Q

MECANISMOS DE VIRULENCIA DA STREPTOCOCCUS PYOGENES

A

ESTREPTOLISINA
CAPSULA - EVASINA
ACIDO LIPOTEICOICO - ADESINA
PROTEINA M - ADESINA + EVASINA

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10
Q

DOENCAS DA STREPTO PYOGENES

A

DOENCAS SUPURATIVAS
FARINGITE
INFECÇÕES DE PELE
FASCITE NECROSANTE
PEPTIDASE C5

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11
Q

FASCITE NECROSANTE

A

BACTERIA CAUSA NECROSE DO TECIDO
DESTRUIÇÃO
VASCULARIZAÇÃO NAO CONSEGUE NUTRIR

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12
Q

ESTRETOLISINA S

A

> BETA HEMOLITICO (DESTRUIÇÃO DE HEMACIAS)
CAUSA HEMOLISE

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13
Q

PROTEINA M

A

ADESINA E EVASINA

EVASINA - IMPEDE OPSONIZACAO

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14
Q

PEPTIDASE C5

A

DEGRADA C5a DO COMPLEMENTO (FATOR QUIMIOTATICO)
INIBE O MAC

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15
Q

ANTIBIOTICOS BETA LACTAMICOS

A

INIBE SINTESE DE PAREDE CELULAR (PEPTIDEOGLICANO -> INTEGRIDADE DA PAREDE BACTERIANA)

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16
Q

TIPOS DE BETA LACTAMICOS

A

PENICILINAS
CEFALOSPORINAS
CARBAPENEMICOS
MONOBACTAMICOS

17
Q

PEPTIDEOGLICANO MAL ESTRUTURADO

A

PAREDE DESTRUIDA PELO COMPLEMENTO

18
Q

MECANISMO DE ACAO BETA LACT

A

1- ANTIMICROBIANO PENETRA NA CELULA
2-NAO É DESTRUÍDO PELAS BETA LACTAMASES PRODUZIDAS POR ALGUMAS BACTÉRIAS
3-SE LIGA E OCUPA/INIBE PBP (PROTEÍNA) -> IMPEDE TRANSPEPTIDAÇÃO QUE FAZ SÍNTESE DE PAREDE

19
Q

SE A BACTERIA TIVER BETA LACTAMASE USA QUAL ANTIBIOTICO

A

ADICIONA CLAVULANATO QUE INUTILIZA A BETA LACTAMASE (EX: AMOX + CLAVULANATO)

20
Q

AÇÚCARES DA PAREDE DA BACTERIA

A

NAG e NAM

MAD (10 decks)

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