Lower Respiratory Tract Infection in Adults Flashcards
What is the UK incidence of pneumonia?
5-11/1000 adult population
What percentage of community acquired pneumonia requires hospitalisation?
Between 22 and 42%
What is the mortality of hospitalised patients with pneumonia?
6-12%
What are some symptoms of pneumonia?
Malaise
Myalgia
Fever
Chest pain
Cough
Purulent sputum
Dyspnoea
What are some signs of pneumonia?
Pyrexia
Tachypnoea
Central cyanosis
Dullness on percussion of affected lobe
Bronchial breath sounds
Inspiratory crepitations
Increased vocal resonance
What investigations are done for pneumonia?
Serum biochemistry, full blood count and C-reactive protein (CRP) test
Chest X-ray
Blood cultures
Throat swab
Urinary legionella antigen
Sputum microscopy and culture
HIV test
What microrganisms are the 3 three for causing pneumonia?
1) Strep pneumoniae (39%)
2) Chlamydophilia pneumoniae (13.1%)
3) All viruses (13.1%)
What is the severity of pneumonia measured by?
CURB 65
What does CURB 65 stand up for?
C confusion
U blood urea > 7
R respiratory rate > 30
B diastolic blood pressure < 60
What is each aspect of CURB 65 given a score of?
0 (low risk and could be treated in the community)
1-2 (hospital treatment usually required)
3 (high risk of death and need for ITU)
What is the treatment for a CURB score of 0-1?
Amoxycillin or clarithromycin/deoxycycline
What is the treatment for a CURB 65 score of 2?
Amoxycillin and clarithromycin or levoflaxacin
What is the treatment for a CURB 65 score of 3-5?
Co-amoxiclav and clarithromycin or levoflaxacin (if penicillin alergic)
What are some things that come before pneumonia?
Aspiration pneumonia
Haematological malignancy
Legionnaires disease
Influenza
Staph pneumonia including PVL toxin
MRSA
HIV
What treatment should be used for pneumonia caused by MRSA?
Vancomycin or linezolid
What are treatment for pneumonia other than antibiotics?
Oxygen
IV fluids
CPAP (continuous positive airway pressure, keeps airways open)
Intubation and ventilation
What does CPAP stand up for?
Continuous positive airway pressure
What are some possible complications of pneumonia treatment?
Septicaemia
Acute kidney injury
Empyema
Lung abscess
Metastatic infection
ARDS (acute respiratory distress syndrome)
What does ARDS stand up for?
Acute respiratory distress syndrome
What is acute respiratory distress syndrome?
Widespread inflammation of the lungs
What is differential diagnosis?
Process of differentiation between two or more conditions which share similar signs or symptoms