Low Back Pain Red Flags Flashcards
Multiple Myeloma General
Most common bone cancer. But still less than 1% of all cancers
Consider in: >50 with chronic LBP and anemia of chronic disease
Order: serum protein electrophoresis for >50 with LBP that don’t respond to care.
MRI is positive. Bone scans are normal
A patient with back pain and recurrent infections in patients over 50. Consider…
Multiple Myeloma OR Spinal Infection
Recognition of red flags and symptoms
Prevention of complications of chiropractic treatment
First step in differential diagnosis of NMS condition
Figure out if it is an injury or disease
Muscloskeletal pain from disease (spine)
Metastatic/primary tumors Spinal Infection Inflammatory diseases (RA, AS, etc.)
Muscloskeletal pain from disease (non-spinal)
Viscerosomatic referral/reflexes (eg, From GI, reproductive, urinary systems)
AAA, endocrine
First step in DDX
Rule out disease
3% of LBP is from serious disease
1% = local cancer or spinal infection
2% = referred pain (usually GI, reproductive system or urinary)
Test characteristics of cancer
Previous cancer: 16-23x
Failure to improve with a month of therapy: 3x
Weight Loss as a Red Flag
Weight Loss (>10 lbs over 3 months)
Sensitivity 15%
Specificity 94%
Better at ruling in
Failure of bed rest to relieve as a Red Flag
Very common in cancer (>90% sensitivity)
Reported in over 1/2 of non-cancer patients - low sensitivity for cancer
Lying down aggravation
Excruciating pain when lying supine, relieved by sitting up or hunched over a table
Possibly from malignant retroperitoneal lymphadenopathy
Secondary to lymphomas and testicular cancer - both are responsive to treatment
Age with LBP as a Red Flag
77-10% of patients were 50 years old or older
Deyo’s study
No patient was found to have cancer and LBP under 50 unless they had:
Prior history of cancer
Unexplained weight loss
Failure of conservative therapy
Night Pain
No longer considered a large concern unless pain is severe, progressive, or unabated by position
42% of pts had night pain and 20% with pain every night
Best questions
Have you ever had cancer?
Yes, think possible recurrence
Have you lost weight recently?
Yes, think cancer
Does bed rest give you any pain relief?
Yes is evidence against cancer.
If pain gets worse then think cancer
When leg symptoms are present
Be more careful especially if:
Female, pediatric, or geriatrics
Bone tumors
Cancer associated with older age and hogher incidence of neurological deficit
Neurological deficits
Primary neoplasm - 55% had objective neurological deficits at the initial visit
20% of patients with spinal malignancy present with neurological deficits
8% with metastatic malignancy have cord compression as the first symptom
Almost 1/3 of prostrate cancer patients have neurological deficits
Clinical strategy for X-Ray
X-Ray any patient with persistent back pain or a neurological deficit