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Rotación 1 > Losartan > Flashcards

Losartan Flashcards

1
Q

Mecanismo de acción

A

Antagonista del receptor AT-1 de angiotensina 2
Activan proteinas Gs, incrementan DAG y IPE, ingreso de Ca
Señalizacion intracelular proliferación e hipertrofia celular
Inhibe procesos de tromboxano A2 y agregacion plaquetaria

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2
Q

Efecto

A

receptor AT2 para provocar vasodilatacion mediada por ON

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3
Q

RAM

A

hipotension, elevacion de enzimas hepaticas, astenia, hiperpotasemia, elevacion de creatinina

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Rotación 1 (31 decks)

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