Loratidina Flashcards

1
Q

MECANISMO DE ACCIÓN

A

Antagonista competitivo, reversible y específico de los receptores histaminérgicos H 1, disminuyendo los efectos sistémicos de la histamina de forma prolongada.

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2
Q

INDICACIONES CLÍNICAS

A

Rinitis alérgica

Urticaria crónica idiopática

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3
Q

Pk

A

VO
A: ↑ con alimentos
M: hepático CYP3A4
E: heces y renal

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4
Q

RAM

A

Xerostomía
Cefalea
Somnolencia
Fatiga

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5
Q

INTERACCIONES

A

Amiodarona:

Puede ↑ el riesgo de prolongación del intervalo QT y torsade de pointes

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6
Q

PRECAUCIONES

A

Epilepsia

Insuficiencia renal y hepática

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7
Q

CONTRAINDICACIONES

A

Porfiria

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8
Q

🤰

A

B

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