Loperamide Flashcards
1
Q
what class is Loperamide under
A
Anti-diarrhoeals
2
Q
What is the mechanism of Loperamide
A
Opioid receptor agonist ==> SMC in intestine ==> Inc. time of food in bowel ==> more water to be absorbed
3
Q
What 3 conditions can Loperamide be given in
A
Diarrhoea
IBS
Short Bowel Syndrome
4
Q
What 3 reasons would you not give Loperamide
A
Blood in stool
Mucous in stool
Acute exacerbation of UC
5
Q
What 2 drugs (types) would you not give Loperamide with
A
Anti-depressants
Opioid Analgesics
6
Q
What are 5 contraindications of Loperamide
A
GI obstruction
Paralytic illeus
Toxic Megacolon
Jaundice
High Risk C.diff infection
