Loop Diuretics Flashcards
1
Q
Mechanism of action
A
Acts in the thick ascending limb of Henle by Na-K-2Cl pumps
2
Q
Excessive used of loop diuretics will cause:
A
- Hypokalemic metabolic alkalosis
2. Ototoxicity
3
Q
Pathologic states that alter response to furosemide
A
- Congestive Heart Failure
- Hepatic Disease and Ascites
- Nephrotic Syndrome
- Infancy/ Prematurity
4
Q
Clinical indications of loop diuretics
A
- Acute pulmonary edema
- Hypercalcemia
- Hyperkalemia
