locomotoro Flashcards
what is the most common locomotor condition?
osteoarthritis
how does it differ from RA?
OA is a degenerative condition from wear and tear over the years whereas RA is AI
who does it affect
F:m 3:1 Over 50s those who have had previous injury wear and tear-overuse from job obesity
define osteoarthritis
degenerative condition where cartiladge becomes damaged and worn
there is the formation of osteophytes
often inflamed and tender on palpation
signs and symptoms
pain on movement background rest pain worse at night inactivity of 30 mins can cause joints to jel crepitus on movement hebeden and bouchards node reduced range of movement
commonly affected sites
cervical and lumbar spine knee foot MTP hand- DIP PIP hip often asymmetrical
investigations
XRAY-LOS loss of JOINT SPACE , osteophytes, subarticular scleross
Elevated CRP
Management
exercises and physiotherapy pain relief-nsaids, coedeine weight loss intraarticular steroid injections heat packs, walking aids TENS surgery-joint replacement
DD
bursitis
gout
psueogout
who does RA affect?
2:1 F:m
5-6th decade
more common in smokers
genetic tendency -HLA-DR4/1
what is it?
autoimmune progressive disorder of the joints-often presents symmetrically - autoantibodies against the synovial joints
the synovial membrane becomes inflammated and infilterated with lymphocytes - forming a plaque on te cartiladge known as PANNUS
presents
inflammation and pain in small joints
symmetrical distribution
pain worse in morning and stiffeness worse at rest
signs- boutinneres , swan neck deformities
ulnar deviation/subuxaltion of joints
boutinneres and swan neck deformities -difference between them
boutinneres- fixed flexion of PIP
swan neck deformities- fixed hyperextension of PIP
diagnostic criteria
4 of the 7 of the following - rheumatoid nodule -rheumatoid factor + - 3 or more joints involved - hand joint involvement radiograph changes -symmetrical -morning stiffness for 6 or more weeks over an hour
areas affected
wrist, below, knee, shoulder, ankle
3 key descriptives
swollen, stiffiness and warm
investigations
clinical examination
rheumatoid factor present In 70%
anti-CRP antibody
Xray shows- swelling, osteopenia, redcued joint space, subulaxtion
management
1st line- DMARDS - Ciclopsorin methotrexate
biologics -▪abatacept
▪rituximab
▪tocilizumab.
surgery
Sulfasazmine
•leflunomide