Localization Flashcards

1
Q

26 y/o w/ difficulty walking & L Leg numbness. 2 days ago foot felt “asleep”, developed numbness over left leg, trunk, arm. Next day noticed R leg and arm weak, unsteady on feet.

PEx: RUE weakness, 5/5 neck/shoulder, 3+ reflexes on R, + Babinski on R. Slow RAM w/ R hand. Vibration & Proprioception decreased throughout R, normal on L. Pain and Temperature decreased on L, normal on R.

Where is lesion?

A

Brown-Sequard. approx C5/C6 on R

Most likely 2/2 demyelinating lesion

NB: bowel/bladder involvement (rectal tone), sensory level can help localize to spinal cord vs. peripheral or brainstem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

60 y/o weakness & atrophy of R hand x 8 months. Progressed. Similar weakness & atrophy of proximal R arm, then L arm. No numbness/pain. R leg weak. Difficult to walk up steps. Muscle twitches. Choking, voice change.

PEx: atrophy of tongue, slurred speech. Atrophy of distal arm and hand, fasciculations. Distal weakness > proximal, R>L. Reflexes 3+. R ankle clonus. Where is lesion?

A

ALS
UMN & LMN signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

ALS DDx

A

1) GBS/AIDP (wouldn’t see UMN signs)
2) Multifocal cord & brainstem lesions (rare, wouldn’t see LMN signs)
3) B12 deficiency, syphilis (but would have marked sensory findings)
4) CIDP
5) Neurmosuclar junction disorder (no UMN findings)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

65 y/o sudden onset chest pain, several minutes later fluent aphasia.

PEx: face symmetric, R superior quadrant anopsia, unable to follow commands, able to imitate, unable to name/repeat, can write (unintelligible). PMH HTN, HLD, CAD, Afib. DDx?

A

Left MCA stroke

Cortical: Contralateral hemiparesis Face & UE>LE, Distal > proximal. Homonymous hemianopsia, aphasia/neglect

Subcortical: face, arm, leg equally involved (w/ internal capsule). Posterior part w/ sensory involvement

Brainstem: Contralateral hemiparesis (w/ cortical spinal tract up to pons), lower pons w/ ipsilateral facial nerve involvement. below pons only arm & leg weakness. Decussation of pyramids in medulla. Crossed findings and cranial nerve common in brainstem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Aphasia types

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

53 y/o M w/ HTN & 3 months chronic neck pain, weakness of L tricep & brachioradialis, s/p C5-C7 fusion. Supine position, pad under R buttock, R leg floated & externally rotated.

Post-Op: painless R foot drop, 0/5 dorsiflexion, 2/5 eversion. Sensory loss in anterolateral R leg and dorsum of foot. DDx

A

Common peroneal nerve neuropraxia

Peripheral nerve lesion (motor, sensory, LMN findings)

Radiculopathy: usually painful, motor involvement through whole root

Plexopathy: similar as above.

Sciatic neuropathy: knee flexion and sensory loss on lateral and bottom of foot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

causes of foot drop

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

25 y/o numbness tingling R hand x2 months, 1st noticed when carrying baby, wakes from sleep. DDx

A

Carpal tunnel
Tinel & Phalen to dx
EMG & NCS gold standard

How well did you know this?
1
Not at all
2
3
4
5
Perfectly