Local anaesthetics Flashcards
1
Q
Bupivacaine
A
Long acting local ana, Amide, for central and preipheral nerve block
2
Q
Intermediate acting LA
A
Lignocaine/ lidocaine, all routes of admin, 2-3 h
3
Q
LAs - adrenaline, vassopressin, felypressin
A
- To prolong anaesthesia and reduce systemic toxicity, drugs can be administered which cause blood vessels to constrict. –Adrenaline, Vassopressin, Felypressin
4
Q
Ester type LAs are metabolized by
A
butyrylyl choline esterase in plasma.
Amides are metabolized more slowly in liver by hepatic oxidases.
5
Q
Differential blockade
A
Type B fibres (sensory-numbness), Type C(pain), Type A(motor)
6
Q
Peripheral nerve block
A
injection close to major sensory nerve trunk
7
Q
Infiltration
A
Injection around nerve endings
8
Q
Central nerve block
A
Spinal: injection into subarachnoid space
Epidural: injection by specific nerve root, more specific anaesthesia
