Local Anaesthesia Pharmacology Flashcards
1
Q
Local Anaesthesia def.
A
drugs which give a reversible loss of sensation in a localized part of the body, when directly applied to nerve tissue of mucous membrane
2
Q
Esters (short prefix + caine)
A
- Cocaine
- Procaine
- Tetracaine
- Benzocaine
3
Q
Amides ( long + vacaine)
A
- Lignocaine/lidocaine
- Bupivacaine
- Levobupivacaine
- Mepivacaine
- Prilocaine
- Etidocaine
- Ropivacaine
4
Q
Nerve block A
A
- Lignocaine
- Procaine
- Bupivacaine
- Tetracaine
- Ropivacaine
5
Q
Spinal Anaesthesia
A
- Lignocaine
- Tetracaine
- Bupivacaine
6
Q
Mechanism of action
A
- Diffusion into nerve fibre
- Blockade of sodium channels
7
Q
Cocaine
A
- Medical use limited to topical use
- Avoid use of epinephrine as it already has vasoconstrictor properties
- Toxicity to the heart may induce rapid lethal cardiac failure
- Overdose results in pyrexia
8
Q
Order of blockade
A
-Autonomic
-Pain
-Temp
-Touch
-Deep pressure
-Motor
(Recovery in reverse order)
