LO1: Impulse Control Disorders Flashcards
What defines an impulse control disorder?
The defining feature is the inability to control or inhibit acting on impulses that may be harmful to self or to others.
What is the impulse response phases?
Impulse or desire ➡️ increased tension ➡️ increased arousal ➡️ commitment of the act ➡️ pleasure, gratification, and tension ➡️ regret, self-reproach, or guilt.
What regions of the brain are involved with impulse control disorders and what are they in charge of?
Nucleus accumbens- involved in urges and impulses
Amygdala- involved in emotional responses
Frontal and prefrontal cortex- involved in risky/compulsive behaviour as well as planning and judgement
What 2 pathways do impulse control disorders affect?
The mesocortical and mesolimbic pathways
Kleptomania
1st clinical cases documented over two centuries ago
Term derived from Greek words meaning “to steal” and “insanity”
Majority of the cases are in females
Characterized by recurrent failures to resist impulses to steal objects
Objects are not desired for their monetary value or personal use
Pleasure or relief results from the act of stealing
What are the three courses of kleptomania?
- Sporadic with brief episode and long periods of remission
- Episodic with prolonged periods of stealing remission
- Chronic and fluctuating
Kleptomania neurobiological influences
Serotonin and dopamine are the main neurotransmitters involved
Opioid and glutamatergic systems
Kleptomania can be a side effect of dopamine agonists used to treat Parkinson’s
Can result in legal problems
Associated with other impulse control disorders and impulse control-related problems, such as impulsive buying
Associated with mood disorders, such as mdd, anxiety disorders, eating disorders (mainly bulimia nervosa), and personality disorders.
SSRIs are first line agents
Pyromania
Documented for at least two centuries
Term derived from Greek words for “fire” and “insanity”
Rare disorder (<1%)
No established age of onset
Majority of cases in males
Found more in those with poorly developed social skills and learning delays
Pyromania
Failure to resist impulses to set fires on multiple occasions
No motivation other than relief of pleasure
Fire setting is episodic
Frequency waxes and wanes
Can result in legal issues
Effective pharmacology not well established
Intermittent explosive disorder (IED)
Sparse epidemiological info available
Lifetime incidence is about 7%
More common in children, adolescents, and young adults
More common in males
IED
Failure to resist aggressive impulses
Result in regular occurrences of verbal or physical aggression
Does or does not result in injury to others or property damage
Degree of outbursts is significantly out of proportion to the precipitating stressor
Revenge for minor injustice is motivation
In children may manifest as severe frequent temper tantrums
Neurobiological influences of IED
Non-specific slowing on EEG
May see reflex asymmetries and delayed speech on exams
Serotonin metabolism may be altered
Treated with anticonvulsants, mood stabilizers, SSRIs, beta-blockers, alpha-2 agonists, and atypical antipsychotics
Trichotillomania
1st described by French dermatologist >100 years ago
Similarities with obsessive-compulsive disorder and Tourette’s
Begins in childhood
Affects up to 3% of the population
More common in females
Trichotillomania
Recurrent pulling out of hair
Results in noticeable hair loss
Continues despite repeated attempts to stop or decrease
Fear of discovery-delay in health care, forego reporting sexual assault
Treated with SSRIs
Two types- binge and sedentary
Gambling Disorder
1-3% of the population
1/3 females and 2/3 males
More prevalent among those whose parents’ had gambling issues and those with deviant peer groups