LMR Flashcards
(379 cards)
TSH Normal Range
-0.5 - 5 Mu/L
T4 Normal Range
0.8 - 2.8
Symptoms of hyperthyroidism can mimic symptoms of
Mania
TSH Down, T3 and T4 Up
Hyperthyroidism
Heat intolerance, agitation, anxiety, irritability, tachycardia, mood swings,
weight loss
Symptoms of hypothyroidism can mimic symptoms of
depression
TSH UP, T3 and T4 Down
Hypothyroidism
Cold intolerance, lethargy, weight gain, decreased libido
What drug - Can cause Spina Bifida (neural tube defect)
- Hepatotoxicity
Depakote - Divalproex Sodium
Patient taking depakote presents with signs of hepatotoxicity. List signs and symptoms
Abdominal pain in
the upper right portion of the abdomen, reddish brown urine, yellowing of the
skin and whites of the eye,fatigue
*Do a liver function test
AST normal range
5-40 U/l
ALT
5-35 U/l
The therapeutic range for valporic acid (total) is
50-125ug/mL.
The toxic level of valporic acid is
greater than 150 ug/uL
Signs of valporic acid toxicity
Disorientation, lethargy, respiratory depression,
nausea/vomiting
Intervention would you do for valporic acid toxicity?
DC med and check valporic acid levels, LFT and ammonia levels
***High yield
Herbal supplement used for anxiety, stress, insomnia
Kava Kava
Kava Kava can cause
Side Effects:
Hepatotoxicity - Can cause liver damage
Use a liver function test
What class of medications to avoid when taking kava kava?
Sedatives because it can cause excessive drowsiness
xanax
clonzapam
lorazepam
phenobarbital
zolpidem
What medication is associated with SJS (stevens-johnson syndrome)?
Lamotrigine (Lamictal)
S/S of Steven-johnson syndrome? signs and symptoms?
Fever, body aches, red rash, peeling skin, facial and tongue
swelling
What Mood stabilizer that causes the least weight gain?
Lamotrigine (Lamictal)
What Antipsychotics that can cause least weight gain?
Z.A.L
Ziprasidone - Geodon
Aripiprazole -Abilify (Least sedating)
Lurasidone - Latuda
Least sedating Antipsychotic?
Aripiprazole (Abilify)
For patients taking antipsychotics that can cause weight gain check routine labs like?
BMI, hip-to-waist ratio, glucose, and lipid panel
Interventions for Management of antipsychotic-induced weight gain (AIWG)?
1.Non pharmacologic interventions include Nutritional counseling and exercise
2.- Pharmacologic interventions consist of switching to another antipsychotic which
has less potential to gain weight (Ziprasidone, aripriprazole, lurasidone -ZAL-)