Liver Pathology Pearls Flashcards
Frequency of liver infarcts and why
RARE, due to the dual blood supply (1/3 hepatic, 2/3 portal)
Exception to rarity of liver infarcts
hepatic artery thrombosis in liver transplant –> major bile ducts only have arterial supply
What does portal vein occlusion cause?
esophageal varices
Most common cause of intrahepatic blood flow obstruction
cirrhosis
most common cause of small portal vein branch obstruction
schistosomiasis
what is associated with obliterative portal venopathy
HIV
What is associated with peliosis hepatis
sinusoidal dilation “blood lakes” (?sex hormones, infection)
Hepatic vein obstruction/thrombosis (name)
Budd-chiari syndrome
What causes veno-occlusive disease (3 things)
1) jamaican bush tea
2) 3 weeks after stem cell transplant
3) cancer
What causes passive congestion of the liver
right-sided heart failure or terminal event
Timeline for acute vs chronic graft vs. host disease
acute = 10-50 days chronic = 100+ days
How transplant is rejected acute vs. chronic
acute = cellular chronic = vascular (leads to vanishing bile duct syndrome)
What does cardiac sclerosis cause?
chronic congestive heart failure
What causes nutmeg liver?
hypoperfusion and retrograde congestion
