Liver histories Flashcards
Presentation of AFLD?
Heavy alcohol consumption, RUQ pain, hepatomegaly. Often undetected, doesnt really prsent with many symptoms. look at risk factors
What can fatty liver lead to?
Cirrhosis
AST and ALT in AFLD?
AST>ALT 2:1
Other key LTFs for diagnosing AFLD?
AST, ALT, ALP raised, GGT raised
Treatment for AFLD?
Alcohol cessation is the only treatment. Alcohol withdrawal services can be useful in this context.
Presentation of acute pancreatitis?
Epigastric/ LUQ pain, radiates to the back, N+V
Causes of acute pancreatitis?
G - gallstones E - ethanol T - trauma S - Steroids M - mumps A - autoimmune S - Scorpion venom H - Hyperlipidemia E - ERCP D - Drugs
Investigations for acute pancreatitis/
Serum amylase and lipase (lipase more specific)
Treatment for Acute pancreatitis?
Crystalloid fluid, NG feeding to avoid pancreatic stimulation, Analgesia, ERCP if jaundice.
NAFLD presentation/typical patient.
No alcohol abuse, truncal obesity, Fatigue, hyperlipidemia, metabolic syndrom, Hepatosplenomegaly, RUQ discomfort
What would the LFTS show for NAFLD?
ALT>AST
Raised ALP
Low albulmin
Treatment for NAFLD?
Diet and exercise, vitamin E, weight loss, Gastric bypass, Liver transplant.
Which is more sensitive to liver problems, ALT, AST or ALP?
ALT
Sytomtoms of biliary colic?
Steady severe pain in the RUQ, resolves within 8 hours, responds to analgesia.
RUQ tenderness, murphys sign, no guarding or rebound.