Liver-General Flashcards

1
Q

3 general metabolic functions of liver

A

Carbohydrate, fat, protein metabolism

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2
Q

Carbohydrate metabolism

A
  • maintains blood glucose
  • glycogen-> glucose (utilization)
  • glucose -> glycogen (storage)
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3
Q

Protein metabolism

A
  • protein -> AA (energy/fat/carbs)
  • detox ammonia from gut
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4
Q

All general liver functions

A
  • carb metabolism
  • fat metabolism
  • protein metabolism
  • synthesis (albumin, globulins, clotting factors, bile)
  • storage (Fe, Cu, glycogen)
  • enzymes detox & metabolize
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5
Q

Kuppfer cells

A
  • destory RBCs and WBCS
  • Hgb -> bilirubin from old red blood cells
  • store excess iron
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6
Q

Clinical signs of hepatic dz

A

Inappetance, anorexia, vomiting +/- diarrhea, jaundice, depression/lethargy, PU/PD, neurological-encephalopathy, coagulopathies, GI ulceration

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7
Q

Clin path changes that occurs in liver dz

A

Increased: liver enzymes, bilirubin, bile acids, blood ammonia, protein(globulins)

Decreased: blood glucose, protein(albumins), clotting factors

Platelet dysfunction

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