Liver gall bladder Flashcards
Liver!
80% parenchyma
20% stroma
thin external capsule of Glisson sends anchoring extension of more delicate CT to support the parenchyma - forms a supportive network of vessels = portal tracts
Hepatic lobules
PT = portal tract (portal vein, biliary duct, hepatic artery)
Six interlobular septae around a CV
Hepatocytes arranged in plates
Sinusoids carry blood towards CV
Hepatic lobule
PT –> CV blood flow
Portal lobule
connects 3 CVs surrounding a PT
Flow of bile from hepatocytes towards PT
Liver acinus
Ellipse with two CVs at each pole
2 PTs and interlobular septa span the centre
Oxygenation of blood - moves towards CV
Central vein
attenuated endothelium
receives blood from sinusoids (*)
deliver blood into larger hepatic vens –> IVC
Yellow: perisinusoidal spaces of Disse underneath sinusoids - exchange of metabolites between hepatocytes & blood
Portal tract
CT stroma surrounding vessels
Red: hepatic arterioles - muscular walls, circular lumina
Purple: major portal venuoles - thin epi
Green: bile ducts, simple cuboidal epi
Yellow: lymphatic channel
Red: hepatic arteriole
Purple: hepatic venuole
Green: bile duct
Blue: Kupffer cell (india ink) - in the endothelial lumen and space of Disse
Yellow: endothelial fenestrations
Pink: sinusoidal endothelial cell
Green: Hepatocyte microvilli
Red: hepatocyte
Kupffer cells stained with India ink in spaces of Disse
Hepatocytes
yellow - hepatic sinusoids
Euchromatic nucleus
Arrows: bile canaliculus
Microvilli in the bile canaliculi - arrow
Tight junctions and desomosomes
Gallbladder
Gallbladder
left to right:
Serosa, muscularis, mucosa
Gallbladder
folds in the mucosa
Gallbladder surface
simple columnar epi
basal nuclei
striated border at its luminal surface
richly vascularized lamina propria
Gallbladder epithelium
Ion transporters at apex
Take in electrolytes and water to concentrate bile
