Liver Function Tests Flashcards
Give me 4 excretory function tests for LFT
- Test for urobilinogen and other bilirubin pigments
- Icterus Index
- Dye Excretion Tests (BSP, ICG)
- Serum Bilirubin
ENUMERATE METABOLIC FUNCTION TESTS
- Carbohydrate Metabolism
- Galactose tolerance test
- OGTT
- Protein Metabolism
- TP, A/G ratio
- cephalin cholesterol floccculation test
- Thymol Turbidity Test
- HIppuric acid test
- Lipid Metabolism
Parenchymal Liver Markers (6)
ALT, AST, AST/ALT (De Ritis Ratio) - LDH, ICC (isocitrate dehydrogenase), OCT (ornithine carbamolytransferase).
Indicators of hepatobiliary disorders- NON- parenchymal markers (4)
ALP, GGT, 5’ Nuleotidase, LAP
Typical lab findings in acute hepatitis of various causes (5)
- Viral
- Alcoholic
- Ischemic/Toxic
- Drug-induced (iatrogenic)
- Autoimmune
PEAK AST and ALT
Ischemic/Toxic
Less than 1 AST/ALT Ratio
Viral, Drug-induced, and Autoimmune
GREATER than 1 AST/ALT ratio
- HIgher AST than ALT
Alcoholic and Ischemic or Toxic
Longest duration among the acute hepatitis causes
Autoimmune
PEAK ALP less than 3 URL
Viral and alcoholic
PEAK ALP LESS THAN 1.5 URL
Ischemic or toxic
PEAK ALP GREATER THAN 3 URL
Drug-induced abd autoimmune
8 TESTS FOR BILIRUBIN
- Evelyn- Malloy
- Jendrassik and grof
- Anino,Ducci and Watson
- Stoner and Wiseberg
- Modified Michaelson
- Thamhauser and Anderson
- Alkaline methanolysis
- Icterus Index
Technique used in Evelyn- Malloy and Jendrassik and Grof
AZOBILIRUBIN TECHNIQUE
What is needed to be mixed so that the IB is solubilize
Methanol- (Evelyn- Malloy)
Caffeine-sodium benzoate (JG)
Calculated from the difference between the TB and DB values
IB fraction
The diazotized product of EM method
BILIRUBIN-DIAZOTIZED SULFANILIC ACID