Liver Flukes: Fasciola hepatica Flashcards
Common name of Fasciola hepatica
- Sheep liver fluke
- Temperate liver fluke
Disease produced by Fasciola hepatica
- Fascioliasis (Sheep)
- Sheep liver rot (Temperate)
MOT of Fasciola hepatica
- Ingestion of Metacercaria encysted on raw edible aquatic plants
- Drinking water with metacercaria
Diagnostic stage of Fasciola hepatica
- Operculated
- Unembryonated egg
1st Intermediate host of Fasciola hepatica
Snail: Family of Lymnaeidae
● L. truncatula
● L. bulmoides
● L. tomentosa
● L. rubiginosa
● L. philippinensis
● L. auricularia
2nd Intermediate host of Fasciola hepatica
Aquatic Plants
- Ipomea obscura (Kangkong)
- Nasturtium officinale (Watercress)
Scientific name for Kangkong
Ipomea obscura
Scientific name for Watercress
Nasturtium officinale
Definitive/Final Host of Fasciola hepatica
Human
Clinical Manifestation of Fasciola Hepatica, there are 6.
- Hepatic Fascioliasis
- Inflammation in biliary epithelium
- Liver atrophy
- Liver cirrhosis
- Liver cancer
- Halzoun/Pharyngeal Fascioliasis
- Ectopic Fascioliasis
What Clinical manifestation of asciola hepatica is this?
Asymptomatic fever, RUQ Abdominal Pains, Inc. PBS for Eosinophil, Hepatomegaly
a. Hepatic fascioliasis
b. Ectopic Facioliasis
c. Halzoun (Pharyngeal fascioliasis)
A
What Clinical manifestation of asciola hepatica is this?
Parasite wanders hematogenously; causes necrosis, abscess, fibrosis (lungs/brain/orbit)
a. Hepatic fascioliasis
b. Ectopic Facioliasis..
c. Halzoun (Pharyngeal fascioliasis)
B
What Clinical manifestation of Fasciola hepatica is this?
Ingesting raw sheep’s liver leading to edema and congestion
a. Hepatic fascioliasis
b. Ectopic Facioliasis
c. Halzoun (Pharyngeal fascioliasis)
C
What Clinical manifestation of Fasciola hepatica is this?
Subcutaneous nodules
a. Skin involvement
b. Biliary obstruction
c. Triad
A
What Clinical manifestation of fasciola hepatica is this?
Cholecystitis, cholangitis, cholelithiasis
a. Skin involvement
b. Biliary obstruction
c. Triad
B
What Clinical manifestation of fasciola hepatica is this?
Sudden onset of high fever, hepatomegaly, marked eosinophilia
a. Skin involvement
b. Biliary obstruction
c. Triad
C
Diagnosis of Fasciola hepatica
- DFS/Stool exam: detection of coproantigens (immunologic method: ELISA, Western blot)
- Duodenal Aspiration
- Serologic test
- NAT (Nucleic Acid Test -> PCR)
- FECT
- Kato-Katz
- Recovery of adult worms during surgery
Treatment for Fasciola hepatica
Triclabendazole
Bithionol
Stain used to be injected in liver flukes to see internal organs
Potassium permanganate or India Ink
Habitat of Fasciola hepatica
- Biliary passages of the liver
- Bile duct
Infectiv stage of Fasciola hepatica
Metacercaria