Liver Disorders Flashcards

1
Q

what is cholestatis

A

impaired bile formation or flow

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2
Q

signs of cholestasis

A
  • fatigue
  • pruritus (itchy skin)
  • dark urine
  • pale
  • jaundice
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3
Q

what relieves cholestatic pruritus

A
  • cholestyramine
  • uroseodeoxycholic acid
  • rifampicin
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4
Q

when does intahepatic cholestasis normally occur and what can it cause

A
  • in pregnancy
  • especially late pregnancy
  • can cause adverse fetal outcomes
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5
Q

tx of intrahepatic cholestasis in pregnancy

A

tx the pruritus that is associated usually tx = ursodeoxycholic acid

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6
Q

what is gallstones

A
  • hard mineral or fatty deposits forming stones in gallbladder bile duct
  • majority = assymptomatic
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7
Q

symptoms of gallbladder that is blocked or irritated

A
  • pain
  • infection
  • inflammation
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8
Q

what can untreated gallstones lead to

A
  • biliary colic
  • cholecystitis
  • colangitis
  • pancreatitis
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9
Q

tx of gallstones if symptoms present

A

surgical removal

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10
Q

pain tx of gallstones

A
  • mild to moderate pain = paracetamol or NSAID
  • severe pain = IM diclofenac
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