Liver & Bowel Disease In Pregnancy Flashcards
1
Q
In which period of pregnancy is hyperemesis gravidarum most common?
A
Trimester 1
2
Q
When is intrahepatic cholestasis of pregnancy most common?
A
Trimester 2 & 3
3
Q
When is acute fatty liver disease of pregnancy most common?
A
3rd Trimester
4
Q
What are the signs & symptoms of AFLP (7)?
A
(1) Nausea & Vomiting
(2) Abdominal Pain
(3) Encephalopathy
(4) Jaundice
(5) Ascites
(6) Polydipsia
(7) Polyuria
5
Q
What is the pharmacological treatment for nausea and vomiting in pregnancy?
A
1st Line: Pyridoxine (Vitamin B6) or pyridoxine-doxylamine (Diclectin)
2nd Line: H1-Blockers (Gravol)
6
Q
How far in advance should MTX be discontinued prior to conception?
A
Discontinue MTX 3 months preconception.
7
Q
Which IBD medications are safe to continue during pregnancy?
A
5-ASA
Azathioprine
Anti-TNF alpha
