Liver and Gallbladder

Question 1

Synthesis of circulating plasma proteins

Answer 1

Albumins/lipoproteins(VLDLs)/Glycoproteins/Prothrombin and fibrinogen

Question 2

Storage and conversion of several vitamins and iron

Answer 2

Vit- A/D/K

Question 3

Degration of drugs and toxins

Answer 3

oxidize or conjugate many water insoluble drugs and toxins

Question 4

Metabolic pathways

Answer 4

Glycogen storage/Cholesterol metabolism/urea synthesis

Question 5

Exocrine function

Answer 5

bile production

Question 6

Endocrine like function

Answer 6

modifies action of hormones released by other organs

• VitD
• Thyroxine
• growth hormone-releasing factor

Question 7

Portal triad

Answer 7

Portal vein
Hepatic artery
Bile duct

Question 8

Order from portal vein

Answer 8

Portal vein–> portal venules–> sinusoids–> terminal hepatic venules–> sublobular veins–> hepatic veins–> IVC

Question 9

Order from Hepatic artery

Answer 9

Hepatic artery–> hepatic arterioles–> sinusoids–> terminal hepatic venules–> sublobular veins–> hepatic veins–> IVC

Question 10

Kupffer cells

Answer 10

Derived from monocytes and are members of the monuclear phonetic system (MPS)

Destroy aged erythrocytes/digest Hb/destroy bacteria

Question 11

Perisinusoidal space (space of Disse)

Answer 11

site of exchange btwn blood and liver cells

Question 12

Ito cells

Answer 12

Hepatic stellate cells–store Vit A

Question 13

With chronic inflammation or cirrhosis

Answer 13

Ito cells lose storage ability and transform into myofibroblasts–synthesis the collagen that results in liver fibrosis

Question 14

What increases flow of bile

Answer 14

CCK
Gastrin
Motilin
Parasym stimulation