Liver

Question 1

What is the differential for bile duct dilatation due to an obstruction?

Answer 1

Stones
Stricture:

Neoplasms - cholangiocarcinoma, gall bladder adeno, pancreatic adeno, metastasis
Post-inflammatory - Pancreatitis, Radiation, Chemo
Inflammatory - AIDS cholangiopathy, biliary parasites, Primary Sclerosing Cholangitis

Question 2

What is the differential for bile duct dilatation due to no obstruction?

Answer 2

Caroli Disease
Choledochal cyst
Recurrent Pyogenic Cholangitis
Primary Sclerosing Cholangitis

Question 3

What is Caroli Disease?

Answer 3

Autosomal recessive ductal plate malformation. Can have saccular or linear dilation of intrahepatic bile ducts.

Complications - Intraductal stones, cholangitis/abscess, liver cirrhosis, cholangiocarcinoma

Question 4

What are regenerative nodules and how are they divided?

Answer 4

Hyperplasia that occurs in cirrhotic livers.

Micronodules - 3mm

They can be sideritic (iron containing)