Liver

Question 1

Hepatitis B after abnormal liver test?

Answer 1

• Start with surface antigen, to find out if infected.
• Treat when actively replicating, so test for viral DNA
• Next, determine extent of inflammation or fibrosis of the liver
  
  • Fibroscan or biopsy, and liver enzymes. Remember that high normal might be inflammed
• E antigen helpfil to kmow when to stop drugs in treatment. (treament only speeds up natural histpey in verticqllyn infected people.
• In acute B, we jist support since 95 percent clear it. 1 in 200 will gwt ALF from too robuat response to virus
• Anti core shpws you cleared it

Question 2

Cirrhosis

Answer 2

• AST above ALT, need to rule out etoh
• Get cholestatic, issues moving bile out, get ALP rise
• Low platelets
  
  • Portal hypertension, splenic vein backs up, enlarges spleen amd get sequesteration of the plaelets
• Then younget lover dysfunction and clinical disfunction, INR goes up with bili, albumin goes down
• ascites varices and HE