Liver

Question 1

Tissue from a pig.

MDx?

A. Passive hepatic congestion

B. Massive hepatic congestion

C. Hepatosis Dietetica

D. Severe Diffuse hepatic necrosis

Answer 1

D.

AKA panlobar necrosis

Question 2

Liver from a horse.

MDx?

Name of disease?

Etiology?

Answer 2

MDx: Chronic passive hepatic congestion

Nutmeg liver

Right-sided congestive heart failure

Question 3

Hepatosis Dietetica is a lesion seen in swine that is caused by ______________. An associated lesion you might see in another area is __________.

Answer 3

Vit. E/Se deficiency

Mulberry Heart disease

Question 4

Canine liver.

MDx?

A possible etiology?

Answer 4

Severe, diffuse, chronic fibrotic hepatitis

(This is END STAGE liver)

A possible etiology is long term use of Anti-epilectic drug therapy (Phenobarbital)

Question 5

Liver of sheep. Note thickened, calcified bile ducts.

What is the most likely etiology?

Answer 5

Fasciola hepatica!

Question 6

Liver abscesses from cow (ooze on cut surface). Most likely BACTERIAL etiology?

Answer 6

Fusobacterium necrophorum

Question 7

Liver from a COW. Most likely etiology?

A. Fasciola hepatica

B. Fascioloides magna

C. Clostridium Chavoei

D. Fusobacterium necrophorum

Answer 7

B.

Fascioloides magna

The black parasitic tracts are the fluke POOP (more correctly known as hematin)

Question 8

In general, for the cow:

Fasciola hepatica causes _______

while fascioloides magna causes _______.

Answer 8

cholangitis (affects bile ducts)

hepatitis (affects liver parenchyma)

Question 9

Canine liver, post-mortem.

Can this be an incidental finding?

And what is the etiology?

Answer 9

Yes!

It indicates that the liver suffered from blunt force trauma in the past and is “fractured”.

The most likely etiology is a hit by car blunt force trauma. If the dog died as a result of the accident, you would likely see a large amount of blood and a hemoperitoneum as well.

Question 10

This 1-2 year old cat presents to you at the RUVC during your seventh semester rotations. She is described as being ADR, not wanting to eat, and is clearly jaundiced. It is noted that she was recently adopted as a stray. CBC/chem tells you she has cholestasis and her eosinophil counts are up.

MOST LIKELY etiology?

Answer 10

Platynosomum fastosum

Common on St. Kitts!!!

Question 11

Tissues from rabbit. Classical presentation.

MDx?

Most likely etiology?

Answer 11

MDx: Proliferative cholangiohepatitis

Eimeria Stiedae

Question 12

Liver from a pig on St. Kitts, post-slaughter.

MOST likely etiology?

Name of condition?

Answer 12

Stephanurus

Milk-spotted liver

Question 13

Liver from pig at slaughterhouse in U.S.

MOST likely etiology?

Name of condition?

Answer 13

Ascarus Suum

Milk Spotted Liver

Question 14

Tissues from a turkey.

MDx?

Etiology?

Answer 14

Multifocal granulomatous hepatitis and diffuse granulomatous typhlitis

Histomonas meleagridis/Heterakis gallinarum

Question 15

Which etiology is associated with causing acute or chronic liver disease in many different animals, and will cause portal fibrosis, biliary hyperplasia, and megalocytosis on histology?

A. Trifolium/Alsike clover

B. Aflatoxins

C. Blue-green algae/Microcystin

D. Pyrrolizidine alkaloids/Sinecio

Answer 15

D. Pyrrolizidines- sinecio, Crotalaria, Tichodesma, Heliotropium

Alsike- NO megalocytosis, also causes photodynamic dermatitis, mostly horses

Blue-green algae- centrilobular to massive hepatic necrosis

Question 16

T or F: Babesia spp. in dogs will cause a pre-hepatic jaundice due to hemolytic anemia as well as cholestasis.

Answer 16

True

Histologically, you will be able to see bile canaliculi distended with bilirubin with Babesiosis.