Liver Flashcards

1
Q

Liver function

A
blood reservoir
coag factors
filters tox: drug kinetics 
bilirubin
protein synthesis
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2
Q

liver asmt

A
jaundice
bruise easy (bleeding)
ascites 
encephalophy 
N/V, abd pain 
ETOH
travel tx, occupation tx
blood transfusion 
hospitalization
esop. varices
bowel habits and color 
current Meds 
wt loss/gain
pruritus
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3
Q

M and M scores liver assessment

A

Child: encephalopy, albumin, bilirubin, ascites, PTT, primary biliary cirrhosis and Nutrition status
MELD

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4
Q

Liver specific labs

A
PTT
AST ALT 
alk phosphate, 
GGT
Ammonia 
5 nucleotidase 
Bilirubin 
Albumin
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5
Q

cholestatic disease

A
biliary obstruction
vit k deficiency 
tx with vit K and FFP
assess: ECG, CO/EF, fluid status
s/s inc CO, inc portal venous pressure-Portal HTN
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6
Q

Hepatitis

A
most common HCV
travel tx
blood transfusion
s/s anorexia, N/V, fever, dark urine, light colored stools, jaundice 
acute--no OR
ascites
Portal HTN 
coags,
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7
Q

Auto-immune hep

A

steroids

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8
Q

Non ETOH fatty liver dz

A
inc type 2 DM
can be asymptomatic
inc LFT
cirrhosis
wt loss can reverse inc LFT
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9
Q

ETOH liver dz

A

ascites, bruising, jaundice, HTN, anorexia, N/V, abd discomfort,
labs: AST, ALT, LFT, coags, albumin, BGL, elytes, T&S
ECG, ECHO-EF

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10
Q

ETOH DT

A
tremors 6-8hr post drink
with in 24hr hallucination, sz
with in 72 hrs DTs 
*high risk for aspiration 
tx benzos
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11
Q

Cirrhosis

A

ascited, jaundice, bleeding, encephalophy, N/V abd pain

??coags, LFT, CBC, BGL??

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12
Q

Liver exam

A

CV: Inc CO, dec SVR, portal HTN, Hyperdynamic circulation
Pulm: dec FRC (bc of ascites)
Fluid status: ascites and edema
CNS: encephalophy

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13
Q

liver dz problem with blood

A

Abn:
coagulation
fibrinolysis
hemostasis

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14
Q

coag disorder lab result with liver

A

inc PT/INR

dec Platelets if

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15
Q

platelet disorder caused by with liver

A

not enough TPO to stimulate platelet making

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16
Q

thrombocytopenia lab result with liver

A

dec platelet

ETOH, hep b

17
Q

Vit K deficiency lab results with liver

A
requires bile to be absorbed in jejunum
necessary for factor 2,7,9,10 protein s and c
from: parenteral nurtition
biliary obstruction
pancreatic insufficiency
malabsorption 
GI obstruction 
increased PTT
18
Q

General liver labs

A
PTT
BGL, elytes
ALT AST alk phos
Ammonia
Platelets
CBC
BAL