Liver

Question 1

Wilson’s disease

Answer 1

symptoms: Kayser-Fleischer rings are visible around the iris
cause: defect in a copper-transporting ATPase -> Copper accumulates and deposits in the liver, cornea, CNS, kidney, heart, blood cells and bones.

Question 2

Criggler-Najjar syndrome

Answer 2

deficiency of the enzyme uridine diphosphate glucuronosyl transferase
type-1, UGT is absent
type-2- UGT is deficient