Lithium Toxicity Flashcards
1
Q
What are some clinical features of lithium toxicity?
A
Coarse tremor
CNS disturbance (seizures, impaired coordination, dysarthria)
Cardiac arrhythmias
Visual disturbance
2
Q
What are some side effects of lithium at a therapeutic dose?
A
Fine tremor
Dry mouth
GI disturbance
Increased thirst
Increased urination
Drowsiness
Thyroid dysfunction
3
Q
What are some investigations for lithium toxicity?
A
Serum lithium levels (GOLD STANDARD)
Electrolyte levels
TFTs
Renal function tests
ECG
4
Q
What is the management of lithium toxicity?
A
Maintaining electrolyte balance
Monitoring renal function
Seizure control
IV fluid therapy and urine alkalisation to enhance excretion
Benzodiazepines for agitation and seizures
Haemodialysis if poor renal function
