Lithium Flashcards
1
Q
Monitoring
A
THYROID - every 6 months Li serum - Weekly - then 3 months when stable BLOOD - 12hours after dose change
2
Q
Toxicity signs
A
N+V Visual disturbances Muscle weakness Fine tremor CNS disturbances - confusion - drowsiness - pack of coordination AV block Polyuria Arrythmias QT prolongation Skin reactions (ulcers)
3
Q
Interactions
A
Diuretics ( thiazide more)
ACE inhibitors/ ARBs
NSAIDs
Antiepileptics
4
Q
Patient advice
A
Same brand
Maintain adequate fluid
Avoid salt changes in diet ( ↓ salt = Li toxicity)
Avoid abrupt withdrawal
- over 4weeks - 3months ( if need to stop abruptly change to atypical antipsychotics/ valproate
