liquid filters Flashcards
Sartopore Platinum 10”, 20”, 30”
Uses -Bioburden reduction -Fill& Finish -Single-Use applications Membrane -hydrophilic PES membrane, pH 1-14 Pros -TwinPleat membrane (66% increased EFA over Sartopore 2) -Coating agent cross-linked and permanently bonded
Sartopore 2 XL
Uses -protein solutions -cell culture media -downstream intermediates e.g. prior to UF/DF, chom Membrane -Tapered membrane 0.8um/0.2um Pros -30% increased EFA over Sartopore 2
Sartopore XLI
Uses -Ophtalmic solutions -concentrated salt/sugar solutions Membrane -Tapered membrane 0.35um/0.2um Pros -Ideally suited for filtration of solutions containing smaller particles.
Sartopore XLM
Uses -peptone, soy, yeast supplemented cell culture media -serum containing cell culture media -cell culture media components Membrane -Tapered membrane 0.2um/0.1um Pros -Especially designed for mycoplasma removal
Sartopore 2
Uses
-Sartopore 2 0.2 um for sterilizing grade filtration of bulk pharmaceutical products and media
-Sartopore 2 0.45um for particle removal, bioburden reduction, prefiltration
Pros
-available in various pore size combinations
Sartobran P
Uses
-plasma fractions (Albumine, IgG, coagulation factors)
-bacterial ad viral vectors
-solutions containing preservatives
-diagnostic reagents
Membrane
-Unique low adsorptive CA (cellulose acetate) membrane, extremely low unspecific binding
Pros
-Highest product yield for blood& plasma products
exceptionally high throughput at low differential pressure
Cons
-Limited chemical compatibility
-pH compatible pH 4-8
Sartolon
Uses
-solvent filtration
-bulk pharmaceutical chemicals
-chemicals and solvents for manufacturing of pharmaceutical products
Membrane
-Only heterogenous double layer Nylon filter
-Pore size 0.45/0.2
Pros
-developed for sterile filtration of antibodies and ADCs
-high chemical compatibility
-solvent resistant
-higher total throughput and flow rates than any other Nylon sterile filter
Cons
-High unspecific adsorption
-pH compatible pH 3-9
