Lipoproteins Flashcards
Chylomicron
Main Lipid: TAG
Apoprotein: B-48
Function: Transports dietary TAG to adipose and other tissues
Chylomicron remnant
Main Lipid: TAG
Apoprotein: B-48
Function: Delivers remaining dietary TAG to liver. Exchanges TAG for Cholesterol ester from HDL; Delivers Cholesterol Ester to the liver.
VLDL
Main Lipid: TAG
Apoprotein: B-100 (A,C,E)
Function: Transports endogenously synthesized TAG to adipose tissue and to skeletal and heart muscle.
Exchanges TAG for Cholesterol Ester from HDL
IDL-VLDL remnant
Main Lipid: TAG and Cholesterol
Apoprotein: B-100 E
Function: Delivers remaining Tag and cholesterol to the liver. Exchanges TAG for cholesterol ester from HDL. Delivers cholesterol ester to liver
LDL
Main Lipid: Cholesterol
Apoprotein: B-100
Function: Delivers cholesterol to liver and other cells
HDL
Main Lipid: Cholesterol
Apoprotein: A’s (C,E)
Function: Accepts cholesterol from peripheral cells, esterifies it, and transports cholesterol esters to liver. Exchanges CE for TAG in VLDL, IDL and chylomicrons.
Atheroprotective and serves as a reservoir for circulating apoproteins that are transported to other lipoprotein molecules.