Lipoprotein Disorders

Question 1

I

Answer 1

Lipoprotein- CM ; TG- Very raised; Xantomas- Eruptive; Clinical- pancreatitis; Etiology- LPL apoC-II; Name -Familial Chylomicronemia Syndrome.

Question 2

IIa

Answer 2

Lipoprotein- LDL ; TG- Normal; Xantomas- Tendon; Clinical- CHD; Etiology- LDLR; Name -Familial hypercholesterolemia (There is also a B-100 mutation syndrome& gain of function of PCSK9)

Question 3

IIb

Answer 3

Lipoprotein- LDL+VLDL; TG- Increased; Xantomas- none ; Clinical- CHD; Etiology- Overproduction of VLDL; Name -Familial Combined Hyperlipidemia

Question 4

III

Answer 4

Lipoprotein- reminants ; TG- Increased ; Xantomas- palmar tubero-eruptive (yellow crap on palms); Clinical-CHD; Etiology apoE2; Name -Familial Dysbetalipoproteinemia

Question 5

IV

Answer 5

Lipoprotein- VLDL ; TG- Increased; Xantomas-none; Clinical- none; Etiology- ?; Name - Familial Hypertriglyceridemia

Question 6

V

Answer 6

Lipoprotein- CM+VLDL; TG- Very Increased; Xantomas- eruptive; Clinical- pancreatitis; Etiology- ?; Name -Familial Hypertriglyceridemia