Lipids (fats) Flashcards

1
Q

What are dominant features of a lipid

A

Hydrogen and carbon

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2
Q

What are lipids

A

Iipids (fats) are molecules made up mainly of carbon and hydrogen and are said to be insoluble in water (due to the non-polarity of the chain). They travel around the blood bound yo specific proteins called lipoproteins

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3
Q

How do lipids travel

A

They travel around the blood, bound to specific proteins called lipoproteins

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4
Q

List examples of lipids

A

Fatty acids, triglycerol, phospholipids and cholesterol

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5
Q

What is the main storage molecules of the body

A

Fats, we store excess energy in the form of lipids (mainly triglycerides)

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6
Q

What are the four functions of lipids in the body

A
  1. Storage of energy (eg. Adipose tissue insulates against body temo changes)
  2. source of energy - twice the energy/gram than protein and carbohydrates (1 gram produced 9 calories of energy)
  3. basic component of cell membrane
  4. chemical messengers - steroid hormones
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7
Q

What are the two types of lipids

A
  1. Lipids with fatty acids included

2. Lipids with fatty acids not included

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8
Q

Examples of lipids with fatty acids

A

truglycerides and phospholipids

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9
Q

Fatty acid included structures

A
  • 8-18 hydrocarbon chain
  • Long hydrocarbon chain with a carboxyl group attached to the end
  • insoluble in water
  • Can either be saturated or unsaturated
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10
Q

characteristics of saturated fatty acids

A
  • only single bonds
  • maximum hydrogens present
  • Single bonds means they have no kinks but have a linear structure. This means they can be easily stacked and tightly. Increasing the MP and BP.
  • solid at room temo
    Eg. Butter and stearic acid (found in steak with 18 carbon atoms)
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11
Q

characteristics of unsaturated fatty acids

A
  • one or more double kinks
  • can either be cis or trans (mostly cis)
  • causes a kink and makes it harder to tightly stack
  • lower MP and BP
  • liquid at room temperature
  • Eg. Margarine
    Oleic acid (has 18 carbon atoms)
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12
Q

Cis isomer

A

Hydrogen atoms on same side producing a kink. more than 99% of fats exist in this cis transformation

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13
Q

Trans isomer

A

hydrogen atoms on opposite sides - more linear structure

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14
Q

Trans fats:

A

Found in processed foods. They are formed by hydrogenation of cis isomers (bombarding cis fats with hydrogens). They have a higher MP and BP and can lead to many cardiovascular diseases.

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15
Q

What are natural fats and oils

A

They are mixtures made up of both saturated and unsaturated fatty acids.
Eg. Olive oil has 84% of unsaturated and 16% of saturated fatty acids

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16
Q

What are essential diietry fats

A
Fats that our bodies do not produce naturally and rely on our consumption of certain foods. 
Eg. Omega 3 (alpha linoleic - 18 carbons and 3 double bonds) 
Omega 6 (linoleic - 18 carbonds and 2 double bonds)
17
Q

What are two examples of fatty acids

A

triglycerides and phospholipids

18
Q

What is triglyceride

A

It is an example of a fatty acids. It is the main lipid storage in the body. These lipids are stored in the adipose tissues. They are composed of a glycerol and three fatty acids

19
Q

What are phospholipids

A

Another example of a fatty acid containing structure. It is also known as glycerophospholipids. It is the most abundant molecule in the plasma cell membrane.. Made up of a glycerol, 2 fatty acids, a phosphate group and a polar molecule

20
Q

Why can’t a membrane be made in a single layer of the phospholipids?

A

Because they are made up of both a hydrophobic and hydrophilic end, causing them to fold in on themselves, creating a micelle.

21
Q

What is the name of lipids that do not contain fatty acids called?

A

Steroids. Including cholesterol, sex hormones and other hormones.

22
Q

What is a steroid?

A

A steroid molecule consists of a characteristic 4 ring hydrocarbon structure.

23
Q

What is the most abundant steroid lipid in the body

A

Cholesterol

24
Q

Where is cholesterol synthesised

A

liver

25
Q

Where is cholesterol consumed from

A

meats, milk and eggs

26
Q

What is a gallstone ?

A

Harden cholesterol stones, caused by the imbalance of bile (helps in digestion of fats). This bile is made by the liver and passed to the gallbladder through a series of tunnels called bile ducts. Over time it becomes more concentrated, helping break down fats faster

27
Q

What is another type of lipids in the body

A

Sex hormones

28
Q

What is testosterone

A

They are the sex hormones in males which are responsible for the development of male organs and male sexual characteristics including muscles, facial hair and sperm formation

29
Q

What is Estradiol?

A

They are the sex hormones for women. They are responsible for the development of sexual characteristics and ovulation

30
Q

What is Progesterone?

A

The sex hormones used to prepare for fertilize egg

31
Q

What are anabolic steroids

A

Synthetic steroids. Synthetic derivatives of testosterone. They have a similar structure but build muscle mass faster and to a greater extent. They are used illegally to build muscle mass but have side effects including infertility, growth effects (short stature), fluid retention, gynecomastia, and liver damage

32
Q

What are some lipids that do not contain fatty acids

A

Cholesterol, sex hormones and other hormones

33
Q

What is Glucocorticoids?

A

A stress hormone that helps relieve stress but can be harmful for the body. They regulate carbohydrates and protein metabolism in the body Eg. Cortisol