Lipids (fats) Flashcards
What are dominant features of a lipid
Hydrogen and carbon
What are lipids
Iipids (fats) are molecules made up mainly of carbon and hydrogen and are said to be insoluble in water (due to the non-polarity of the chain). They travel around the blood bound yo specific proteins called lipoproteins
How do lipids travel
They travel around the blood, bound to specific proteins called lipoproteins
List examples of lipids
Fatty acids, triglycerol, phospholipids and cholesterol
What is the main storage molecules of the body
Fats, we store excess energy in the form of lipids (mainly triglycerides)
What are the four functions of lipids in the body
- Storage of energy (eg. Adipose tissue insulates against body temo changes)
- source of energy - twice the energy/gram than protein and carbohydrates (1 gram produced 9 calories of energy)
- basic component of cell membrane
- chemical messengers - steroid hormones
What are the two types of lipids
- Lipids with fatty acids included
2. Lipids with fatty acids not included
Examples of lipids with fatty acids
truglycerides and phospholipids
Fatty acid included structures
- 8-18 hydrocarbon chain
- Long hydrocarbon chain with a carboxyl group attached to the end
- insoluble in water
- Can either be saturated or unsaturated
characteristics of saturated fatty acids
- only single bonds
- maximum hydrogens present
- Single bonds means they have no kinks but have a linear structure. This means they can be easily stacked and tightly. Increasing the MP and BP.
- solid at room temo
Eg. Butter and stearic acid (found in steak with 18 carbon atoms)
characteristics of unsaturated fatty acids
- one or more double kinks
- can either be cis or trans (mostly cis)
- causes a kink and makes it harder to tightly stack
- lower MP and BP
- liquid at room temperature
- Eg. Margarine
Oleic acid (has 18 carbon atoms)
Cis isomer
Hydrogen atoms on same side producing a kink. more than 99% of fats exist in this cis transformation
Trans isomer
hydrogen atoms on opposite sides - more linear structure
Trans fats:
Found in processed foods. They are formed by hydrogenation of cis isomers (bombarding cis fats with hydrogens). They have a higher MP and BP and can lead to many cardiovascular diseases.
What are natural fats and oils
They are mixtures made up of both saturated and unsaturated fatty acids.
Eg. Olive oil has 84% of unsaturated and 16% of saturated fatty acids
What are essential diietry fats
Fats that our bodies do not produce naturally and rely on our consumption of certain foods. Eg. Omega 3 (alpha linoleic - 18 carbons and 3 double bonds) Omega 6 (linoleic - 18 carbonds and 2 double bonds)
What are two examples of fatty acids
triglycerides and phospholipids
What is triglyceride
It is an example of a fatty acids. It is the main lipid storage in the body. These lipids are stored in the adipose tissues. They are composed of a glycerol and three fatty acids
What are phospholipids
Another example of a fatty acid containing structure. It is also known as glycerophospholipids. It is the most abundant molecule in the plasma cell membrane.. Made up of a glycerol, 2 fatty acids, a phosphate group and a polar molecule
Why can’t a membrane be made in a single layer of the phospholipids?
Because they are made up of both a hydrophobic and hydrophilic end, causing them to fold in on themselves, creating a micelle.
What is the name of lipids that do not contain fatty acids called?
Steroids. Including cholesterol, sex hormones and other hormones.
What is a steroid?
A steroid molecule consists of a characteristic 4 ring hydrocarbon structure.
What is the most abundant steroid lipid in the body
Cholesterol
Where is cholesterol synthesised
liver
Where is cholesterol consumed from
meats, milk and eggs
What is a gallstone ?
Harden cholesterol stones, caused by the imbalance of bile (helps in digestion of fats). This bile is made by the liver and passed to the gallbladder through a series of tunnels called bile ducts. Over time it becomes more concentrated, helping break down fats faster
What is another type of lipids in the body
Sex hormones
What is testosterone
They are the sex hormones in males which are responsible for the development of male organs and male sexual characteristics including muscles, facial hair and sperm formation
What is Estradiol?
They are the sex hormones for women. They are responsible for the development of sexual characteristics and ovulation
What is Progesterone?
The sex hormones used to prepare for fertilize egg
What are anabolic steroids
Synthetic steroids. Synthetic derivatives of testosterone. They have a similar structure but build muscle mass faster and to a greater extent. They are used illegally to build muscle mass but have side effects including infertility, growth effects (short stature), fluid retention, gynecomastia, and liver damage
What are some lipids that do not contain fatty acids
Cholesterol, sex hormones and other hormones
What is Glucocorticoids?
A stress hormone that helps relieve stress but can be harmful for the body. They regulate carbohydrates and protein metabolism in the body Eg. Cortisol