Lipids Flashcards
What is the Low Carb Lipid TRIAD
is is the same as the Lean Mass Hyper-responders?
High LDL & HDL
Low triglycerides
Yes!
Barlett 2016
In the presence of High LDL-C and Low TG (<100)
The OR for CVD was the same for
LDL < 100 (OR 0.6)
LDL > 100 (OR 0.7)
LDL > 130 (OR 0.7)
Copenhagen Male Study
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/647239
LDL below or above 170
Risk of DVD nearly identical on High HDL and Low TG
what is CIMT
carotid intima-media thickness test
- extent of carotid atherosclerotic vascular disease
- measures thickness of the inner two layers of the carotid artery—the intima and media—and alerts physicians to any thickening when patients are still asymptomatic
Thyroid hormone
upregulates OR down-regulates
the LDL receptor?
What are the implications? (e.g. hypothyroidism)
Upregulates
“you don’t treat hypercholesterolemia until you’ve treated hypothyroidism”
A long time ago thyroid hormone was used to treat FH! (Familial Hypercholesterolemia)
Does fasting increase or decrease LDL?
Not clear, Dave Feldman would say it increases, Peter Attia has seen it generally stay the same or go down
What is the main index of glycemic variability?
mean amplitude of glycemic excursion (MAGE)
used to gauge the degree of glucose level fluctuations
What is Apolipoprotein B?
Apolipoprotein B is the primary apolipoprotein of
- chylomicrons
- VLDL
- IDL
- LDL particles
It is responsible for carrying lipids, including cholesterol, around the body (within the water outside cells) to all cells within all tissues. While all the functional roles of ApoB within the LDL (and all larger) particles remain somewhat unclear, it is the primary organizing protein (of the entire complex shell enclosing/carrying fat molecules within) component of the particles and is absolutely required for the formation of these particles. What is also clear is that the ApoB on the LDL particle acts as a ligand for LDL receptors in various cells throughout the body (i.e., less formally, ApoB indicates fat carrying particles are ready to enter any cells with ApoB receptors and deliver fats carried within into the cells).
what are MUFAs?
Examples
Monounsaturated fatty acids
- Olive oil
- Avocados
- Almonds, cashews and peanuts
Saturated fatty acids:
how many double bonds between the carbons in their chains do they have?
Saturated fats DON’T have any double bonds between the carbons in their chains!!!
Monounsaturated fats:
how many double bonds between the carbons in their chains do they have?
Monounsaturated fats have ONE double bond between carbons in their chains.
Polyunsaturated fatty acids:
how many double bonds between the carbons in their chains do they have?
MORE THAN ONE
Fatty acid chain length:
- Short-chain fatty acids: How many carbons do they have?
- Give example foods
- 5 or fewer carbons
- butter and cream
Medium-chain fatty acids
ARE THE SAME AS
medium-chain triglycerides = MCTs !!!
Fatty acid chain length:
Medium-chain fatty acids: How many carbons do they have?
Give example foods
Medium-chain fatty acids (also known as medium-chain triglycerides or MCTs)
have 6-12 carbons
- coconut oil
- MCT oil
- butter and cream also contain a small amount of MCTs.
Fatty acid chain length:
Long-chain fatty acids: How many carbons do they have?
Give example foods
- 13 or more carbons
- Most of the fats in food are made up of long-chain fatty acids.
- meat
- fish
- dairy
- nuts & seeds
- avocado
- olives
Tiende a evitar y usar el humor como mecanismo de distraccion
He tends to deflect with humour and
intellectual responses
Voy a intentar conectar la llamada
I’m trying to PATCH YOU IN
Me he dado cuenta de que sueles ponerte de victima
I have recognized that
you always end up painting a story where you are the ultimate victim
EL le reprendio (a ella) por aver revelado el secreto
He CHIDED her for revealing the secret to me
reganyar
scold or rebuke.
“she chided him for not replying to her letters”
Si te va bien con la dinamica familiar…
If it fits with family flow…
Un momento en los labios,
para siempre en las caderas
A moment on the lips,
forever on the hips
Para que no crean que soy un GUARRO
(Cambell)
So they don’t think I’m a SLOB
a person who is lazy and has low standards of cleanliness.
“he’s a slob and expects others to clean up after him”
SUcumbiste al azucar?
(Molly)
Did you yield to the sugar?
En el fondo no les voy a denunciar, era una exageracion.
(Christian P re cannabis clinic)
I wouldn’t really sue them: that is hyperbole.
Thierry Hertoghe es un temerario
Thierry Hertoghe is a MAVERICK
Diferencia maverick vs daredevil
Maverick: dissident
MAVERICK: temerario
Dr Sandeep Bolia:
Tam prescribes PEDs
PED - a performance-enhancing drug
Dr Sandeep Bolia:
Tam SHOOTS FROM THE HIPS
Impulsiva, dice las cosas sin pensar
Dr Sandeep Bolia:
Zen “THEY SAIL CLOSE TO THE WIND”
What they do is bordering on dodgy - DANGEROUS
Dr Sandeep Bolia:
Me tengo que ir.. (informal)
I may have to shoot
Es un poco inferiorico (1 expresiones)
He’s not the BRIGHTEST OF THE BUNCH
He is not the SHARPEST BLADE IN THE KITCHEN
(rather than sharpest knife in the drawer)
No quiero ser desconsiderado…
I don’t want to be INCONSIDERATE…
Consegui limpiar mi nombre
“Dr Patel OCD”
I was vindicated
When you are vindicated, your name is cleared
Northener saying
“todo el mundo es raro”
“there’s nothing as strange as some people”
(Adam)
“Nowt as queer as folk”
Meaning people can be strange. It’s a Yorkshire saying.
