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FTM week 1-3 > Lipids > Flashcards

Lipids Flashcards

1
Q

phosphatidylcholine

A

glycerophospholipid

outer leaflet

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2
Q

phosphatidyl serine

A

glycerophospholipid

exposed to surface of apoptotic cells - move from inner to outer

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3
Q

cardiolipin

A

glycerophospholipid

abundant in INNER MITO MEMBR ONLY

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4
Q

Dipalmitoylphosphatidylcholinde (DPPC)

A

-glycerophospholipid
-part of surfactant, low level in neonates so incr respiratory distress
L/S > 2 –> fetal lung mature
L/S < 1.5 –> not mature, incr risk RDS

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5
Q

Plasmalogens and platelet activating factor (PAF)

A
  • glycerophospholipid

- ether instead of ester linkage

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6
Q

glycerophospholipid xture

A

glycerol backbone with 3 branches: 1 sat FA, 1 unsat FA, and base with phosphate

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7
Q

sphingophosphylipid

A

is a type of phospholipid

-sphingomyelin

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8
Q

sphingomyelin

A
  • sphingophospholipid
  • outer leaflet
  • lipid raft
  • abundant in MYELIN SHEATH
  • sphingosine backbone with 2 branches: FA and choline w phosphate
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9
Q

ceramine

A

sphingosine backbone with 1 FA

-used in sphingomyelin (sphingophospholipid) and all glycolipids

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10
Q

glycolipids

A
  • outer leaflet - form glycolax
  • lipid raft
  • impt in myelin sheath
  • cerebroside, sulfatide, globoside, ganglioside
  • also glycosphingolipids/ sphingoglycolipids
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11
Q

oleic acid

A

MUFA

  • olive oil
  • 18C
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12
Q

Cholesterol

A
  • lipid raft
  • ampipathic
  • derived lipid
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13
Q

Saturated FAs

A
  • short chain, med and long chain

- no double bond

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14
Q

palmitic acid

A

long chain saturated FA

-16 C

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15
Q

steric acid

A

long chain saturated FA

  • 18 C
  • synth oleic acid
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16
Q

what are the omega 6 FAs

A
  • linoleic (C18) *essential 2 double bond

- arachidonic acid (C20)- 4 double bond – synth eicosanoids (proinflammatory)

17
Q

What are the omega-3 FAs

A

alpha linolenic acid (ALA) (C18) *essential, 3 double bond

  • eicosapentanoic acid (EPA), (C20) 5 double bond (antiinflammatory, cardio protective)
  • docasahexanoic acid (DHA) (C33) 6 double bond
18
Q

Which FAs have increased fluidity

A

arachidonic acid and docosahexanoic acid (DHA)

bc incr double bond

19
Q

cerebroside

A

glycosphingolipid

-ceramide + monosacch

20
Q

sulfatide

A

glycosphingolipid

-ceramide + monosacch + sulfate

21
Q

globoside

A

glycosphingolipid

-ceramide + oligosacch

22
Q

ganglioside

A

glycosphingolipid

-ceramide + oligosacch + NANA (9C sugar)

FTM week 1-3 (4 decks)

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