Lipids Flashcards
What is a lipid + their properties?
- generalised term for fats and oils
- contain carbon, hydrogen and oxygen
- proportion of O to C + H is smaller than carbohydrates’
- insoluble in water but soluble in organic solvents
What are some roles of lipids?
- phospholipids make up plasma membrane
- provide energy -> when oxidised provide 2x energy as carbs
- insulators, slow heat conductors so retain body heat
- some hormones are lipid based e.g testosterone
- offer protection of delicate organs
What is the structure of triglycerides?
3 fatty acids combined with a glycerol
What is a fatty acid?
Long chain hydrocarbons containing a COOH group
What are the differences between a saturated and unsaturated fatty acid?
-Saturated = hydrocarbon has only single bonds
- form saturated lipids which are solid at room temp
_Unsaturated = hydrocarbon chain has at least 1 double bond
- forms unsaturated lipids = liquid at room temp
How are triglycerides formed?
3 condensation réaction between the glycerol and the 3 fatty acids, forming 3 ester bonds
What is cholesterol’s properties?
- insoluble in water
- must combine with proteins to be transported in the bloodstream, forming lipoproteins
Describe the formation and function of low-density lipoproteins
- triglycerides from fats in diet combine w/ cholesterol and proteins to form LDLs, which transport cholesterol to body cells
- circulate in bloodstream and bind to receptor cells on membranes before being taken in
- excess LDLs overload membranes, means high cholesterol levels in blood which may be deposited into artery wall causing an atheroma
Describe the formation and function of high density lipoproteins
- higher % of protein + less cholesterol; are made when triglycerides from fats combine with cholesterol and proteins
- HDLs transport cholesterol from body tissues to the liver where it is broken down
- lowers blood cholesterol levels + helps removing fatty plaques
What diet increases/decreases LDLs and HDLs?
- saturated fat diet = increases both LDLs and HDLs but more LDLs
- unsaturated fat in diet = decreases both LDL and HDL levels
Draw/Describe the formation reaction for a triglyceride
3x Fatty acid tails with HO-C=O (carboxyl groups) attached, glycerol = 3 carbons each bonded to H, H and OH and other C