Lipid-lowering Drugs (basics)

Question 1

what treatment strategies are used for dyslipidaemias?

Answer 1

1) diet/ lifestyle changes
2) drugs used in hyperlipidemias

Question 2

what drug classes are used in hyperlipidemias?

Answer 2

1) omega-3 acid ethyl esters
2) PCKS9 inhibitors
3) fibrates (fibric acid derivatives)
4) bile acid binding resins
5) HMG-CoA reductase inhibitors (“statins”)
6) inhibitors of intestinal sterol absorption

Question 3

name 4 HMG-CoA inhibitors

Answer 3

“-vastatin”s
1) atorvastatin
2) pravastatin
3) simvastatin
4) fluvastatin

Question 4

name 2 PCSK9 inhibitors

Answer 4

“-ocumab”s
1) evolocumab
2) alirocumab

Question 5

name 2 fibrates (fibric acid derivatives)

Answer 5

1) gemfibrozil
2) fenofibrate

Question 6

name 1 omega-3-acid ethyl ester

Answer 6

omacor

Question 7

what are the 2 constituents of omacor?

Answer 7

eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) ethyl esters

Question 8

name 1 bile acid binding resin

Answer 8

cholestyramine

Question 9

name 1 inhibitor of intestinal sterol absorption

Answer 9

ezetimibe