link reaction and anaerobic

Question 1

outline of link

Answer 1

pyruvate converted to acetyl CoA

irreversible reaction
occurs in matrix of mitochondria
- pyruvate transferred from cytoplasm

Question 2

glucose oxidation

Answer 2

glycolysis releases some but not all energy in glucose

much more energy released through complete oxidation of glucose to CO2 and water

occurs in TCA cycle

Question 3

process of link reaction

Answer 3

oxidative decarboxylation reaction

pyruvate reacts with CoA
thiol group joins to acetyl group (from pyruvate)
= acetyl CoA

catalysed by pyruvate dehydrogenase

decarboxylation (CO2 removed) and oxidation of pyruvate
NAD reduced to NADH

Question 4

fate of pyruvate under anaerobic conditions

Answer 4

NADH oxidised to NAD
lactate produced

CO2 released
decarboxylated to acetaldehyde
NADH oxidised to NAD
reduced to ethanol

Question 5

products of link reaction

Answer 5

2 molecules of acetyl-CoA

3 ATP/NAD through oxidative phosphorylation
total = 6 ATP