Link Reaction

Question 1

In the presence of molecular oxygen?

Answer 1

Transport protein embedded in inner mitochondrial membrane transports pyruvate from cytosol into mitochondrial matrix

Question 2

3 stages?

Answer 2

1. Decarboxylation
   - one molecule is removed from pyruvate (3C)
2. Dehydrogenation
   - transfer of H+, yielding NADH
3. Oxidation
   - coenzyme A is added to remaining 2C acetyl group-> acetyl CoA;

-converting of pyruvate to acetyl CoA @mitochondrial matrix is catalysts by pyruvate dehydrogenase

Question 3

What happen to acetyl CoA

Answer 3

Moves into Kerb cycle