lineage of blood cells Flashcards
1
Q
in bone marrow, are many stem cells able to produce all blood cell types
A
a very small number of self-renewing pluripotent stem cells are capable of giving rise to all blood cell types, including lymphocytes
2
Q
what do haemopoietic stem cells give rise to
A
colony forming units (CFU’s)
3
Q
what has the potential to give rise to all blood cell types except lymphocytes
A
CFU-GEMMs
4
Q
name all blood cell types, except from lymphocytes, and what each develop in response to
A
granulocytes, erythrocytes, monocytes and megakaryocytes
- each develop in response to different cytokines and hormones
5
Q
how are erythrocytes formed
A
intermediate CFUs - burst-forming units (BFUs) - erythrocytes