Limb Ulceration Flashcards

1
Q

What are the causes of leg ulceration

A
  • venous hypertension
  • arterial disease
  • neuropathic
  • neoplastic
  • vasculitis
  • infection
  • haematological
  • drugs
  • other
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2
Q

What are the different types of leg ulcers

A
  • Venous ulcers
  • arterial ulcers
  • neuropathic ulcers
  • pressure ulcers
  • diabetic ulcers
  • ischeaemic ulcers
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3
Q

What causes venous ulcers

A
  • venous ulcers are the result of sustained venous hypertension in the superficial veins due to incompetent valves in the deep perforating veins or to previous deep vein thrombosis
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4
Q

What are venous ulcers associated with

A
  • oedema of the lower legs
  • venous eczema
  • brown pigmentation from haemosiderin
  • varicose veins
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5
Q

What is the management of venous ulcers

A
  • high compression bandaging and leg elevation to reduce venous hypertension
  • doppler studies should be done before compression to exclude significant arterial disease
  • diuretics can reduce the oedema
  • antibiotics only necessary for overt bacterial infection
  • opiate pain medication if required
  • ulcer dressings
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6
Q

Where are arterial ulcers

A
  • present as punched out, painful ulcers higher up on the leg or on the feet
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7
Q

What is the clinical presentation of arterial ulcers

A
  • clinically the leg is cold and pale
  • absent peripheral pulse
  • arterial bruits
  • loss of hair
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8
Q

What is the management of arterial ulcers

A
  • keep the ulcer clean and covered

- adequate analgesia and vascular reconstruction if appropriate

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9
Q

What causes neuropathic ulcers

A
  • tend to be over pressure areas of the feet such as the metatarsal heads owing to repeated trauma
  • most commonly found in diabetics due to peripheral neuropathy
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10
Q

what causes arterial ulcers (ischaemic ulcers)

A

Arterial leg ulcers occur as a result of reduced arterial blood flow and subsequent tissue perfusion.

Three mechanisms involved in the pathophysiology :

  • (a) extramural strangulation,
  • (b) mural thickening or accretion
  • (c) intramural restriction of blood flow
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11
Q

What causes diabetic ulcers

A

Diabetic ulcers are most commonly caused by: poor circulation. high blood sugar (hyperglycemia) nerve damage

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12
Q

What is the management of pressure ulcers

A
  • bed rest with pillows and fleeces to keep pressure of bony areas and to prevent friction
  • air filled cushions for patients in wheelchairs
  • special pressure relieving mattresses and beds
  • regular turning but avoidance of pressure on hips
  • adequate nutrition
  • treatment of underlying cause
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13
Q

How can you prevent ulcers

A
  • identify at risk patients
  • use of the Norton scale to identify those who are most at risk

Primary prevention

  • loose weight
  • compression stockings
  • treat underlying cause such as varicose veins
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14
Q

if the skin ulcer is superior to the medial malleolus what type of ulcer is it likely to be

A
  • venous ulcer
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15
Q

If the skin ulcer is around the sacrum, greater trochanter, or heel what type of ulcer is it likely to be

A
  • pressure sore (decubitus ulcer)
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16
Q

What does an ischaemic ulcer feel like

A
  • ulcer and surrounding tissue are cold
17
Q

When does an ulcer become a chronic ulcer

A

4 weeks old

18
Q

What does the shape of the ulcer tell you about what has caused it

A
  • Oval, circular → cigarette burn
  • Serpiginous → Klebsiella granulomatis
  • Unusual shape → mycobacterial infection (eg cutaneous TB or Scrofuloderma)
19
Q

what does the edge of the ulcer tell you about it

A
  • Shelved/sloping = healing
  • punched out = syphilis or ischaemic
  • Rolled/everted = malignant
20
Q

What does the discharge tell you about the ulcer

A
  • watery discharge = TB

- bleeding = malignancy

21
Q

What does associated lymphadenopathy suggest

A
  • suggests infection or malignancy
22
Q

What does decreased sensation around the ulcer suggest

A
  • implies neuropathy
23
Q

What do arterial ulcers look like and what are they common in

A
  • punched out appearance
  • full thickness defect
  • common in DM
  • can occur anywhere in the extremities
24
Q

What do venous ulcers look like and where are them

A
  • accompanied by varicose veins
  • distal leg and ankle
  • painful and heavily exudative
  • often recurrent
  • exhibit varying depths even within 1 ulcer
  • can become huge
25
Q

where and why do pressure ulcers occur

A
  • usually occur on bony prominences

- occur because pressure obstructs superficial blood flow

26
Q

What is Marjolin’s ulcer

A
  • Squamous cell carcinoma
  • occurring at sites of chronic inflammation e.g. burns, osteomyelitis after 10-20 years
  • mainly occur on the lower limb
27
Q

where do neuropathic ulcers occur and why do they occur

A
  • they commonly occur over plantar surface of metatarsal head and plantar surface of hallux
  • plantar neuropathic ulcer is the condition that most commonly leads to amputation in diabetic patients
  • due to pressure
  • management includes cushioned shoes to reduce callous formation
28
Q

What is pyoderma gangrenous associated with

A
  • associated with inflammatory bowel disease
29
Q

What does pyoderma gangrenosum look like and where does it occur

A
  • can occur at stoma sites

- erythematous nodules or pustules which ulcerate

30
Q

What investigations do you carry out of Ulcers

A
  • note appearance
  • ABPI - arterial or venous insufficiency
  • biopsy - to assess for vasculitis and malignant changes
31
Q

What is the management of ulcers

A

Treat cause and focus on prevention

Bandaging

  • Charing Cross - 4 layer compression bandaging preferred (ABPI>0.8)
  • Honey dressings for mild-moderate burns
  • negative pressure wound therapy (VAC) for diabetic ulcers

Surgery, larval therapy, hydrogels
- used to debride sloughy necrotic tissue

Antibiotics
- only if infection - does not improve healing