LGBTQIA+ Health Flashcards

1
Q

Intersectionality

A

Having more than one social identity creates a whole

I.E: trans person of color vs cis person of color

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2
Q

Implicit bias
What to do if you have them?

A

Having an opinion or stereotype about a person or group of people without realizing it

Be aware of your own and reflect on them

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3
Q

Informed consent vs Standards of Care

A

Informed: patient decides what type of care is appropriate
Standards of care: mental health provider decides what tpye of care is appropriate

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4
Q

What to consider before starting hormone therapy for transitioning

A
  • Think about the patient’s goals of treatment
  • Research costs w/ and w/o insurance
  • Don’t put off starting hormone therapy until other illnesses are under control
    • Very few absolute contraindications to starting hormone therapy, only if the condition is extrememly unstable for the patient
    • I.E: HIGH LFTs, breast cancer (estrogen therapy)
  • Gender history: what hads it been like for you to think about your gender/gender identity?
  • Managing expectations - BE REALISTIC
    • Go over expected timeline/changes
    • what hormones don’t do
  • Does the patient have support?
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5
Q

Irreversible changes (testosterone therapy)

A
  • Clitoris grows
  • Body hair becomes darker and thicker
  • Voice deepens
  • Facial hair grows
  • Head hair becomes thinner
    • “Male pattern baldness”
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6
Q

Reversible changes (testosterone therapy)

A
  • Body fat redistibutes - abd + waist
  • Muscle mass increases
  • Acne increases
  • Skin becomes oiler
  • Libido increases
  • Menstruation stops 6 months in
    • bleeding can get irregular or unusual when starting T
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7
Q

Three BIGGER things that testosterone DOES NOT DO

A
  • Increase height (if puberty is complete)
  • Shrink breasts
  • Change vocal intonation - pronunciation (can practice changing)
  • Change bone structure
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8
Q

Testosterone therapy risks

A
  • Heme: Erythrocytosis → clot risk
  • GI: liver inflammation → only check LFTs if have s/s
  • CV: teach lifestyle modifications to decrease risk
    • HTN, HLD, MI, stroke
  • Endocrine: only check for insulin resistance if need to
  • Reproductive: infertility, vaginal dryness/atrophy
  • Psychosocial
    • Destabilization of certain mood disorders: bipolar + schizophrenia losing stability when starting T → dose daily instead of weekly
    • Social consequences: transphobic society
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9
Q

Causes of pelvic pain in transmasculine patients

A
  • R/O other DXs first and treat
  • Vaginal atrophy - use smallest speculum for exam
    • Low estrogen state - similar to menopause, post-partum lactation, cancer treatment
    • Can cause pain on its own, or predispose to other diagnoses
    • BV, UTI, cervicitis - TX
    • Trauma from penetration or friction
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10
Q

Treatment for pelvic pain in transmasculine patients

A

Vaginal estrogen
* Localized dose
* Not systemically absorbed, short course
* Will not cancel out Testosterone therapy tx
* Creams > tablets

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11
Q

Treatment for cyclic pelvic pain in transmasculine patients

A
  • Can be caused by T INJ and/or penetration/orgasm
  • Switching from INJ → transdermal if correlated w/INJ timing
  • Pelvic floor PT
  • Hysterectomy/endometrial ablation
  • General pelvic pain treament options (consider trauma/PTSD w/dysphoria)
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12
Q

Bleeding in transmasculine patients
Differentials

A
  • Pregnancy
  • Fibroids
  • Endometrial polyps
  • Cervicitis
  • Malignancy
  • PCOS
  • Thyoid dysfunction
  • Eating disorder
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13
Q

Delaying T if patient shows irregular bleeding?

A
  • Depends, wait until full work-up is done to decide delaying
  • Weight risks/benefits of delaying T
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14
Q

Diagnostic, dose work-up for persistent bleeding after 6-12 months on T

A
  • Consider body physique for testosterone dosing
    • Larger build → aromatizing testosterone → estrogen tissue (estradiol)
      • May help to decrease T
    • Missing/skipping INJs d/t financial cost
  • Labs: Testosterone, FSH, LH
    • If both WNL + testosterone in male range → further workup
      • Endometrial polyps, endometrial hyperplasia, polyps, maligancy
  • Imaging: Pelvic U/S, endometrial biopsy, transabdominal U/S alone (less invasive)
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15
Q

Treatments for bleeding in transmasculine patients

A
  • Adjust T
  • Add progestin
  • Hysterectomy
  • Endometrial ablation
    • Higher T
    • BC, Depoprovera, IUD, etc.
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16
Q

Testosterone therapy medication forms and implications of each

A
  • INJ: T cypionate + T enthanate
    • Qweekly or 2x dose Q2weeks
    • IM, SQ (common - smaller needle)
    • Compounded in oil - sesame - check allergy
  • Gel: Avoid contact w/others after applying (Qday)
  • Patch: may cause skin irritation or fall off (Qdaily)
  • Implant: Q3-6months (Testopel)
    • In SQ fat of hip area
    • Dissolves over time (do not need to be removed)
  • Other meds
    • Topical estrogen cream or Estring for genital atrophy
    • Finasteride for male pattern baldness
      • May cause external genitalia abnormalities in male fetuses (no crushed/broken tablets for ppl who might be pregnant)
17
Q

Testosterone therapy monitoring
Timing
Labs

A
  • At 3, 6, 12 mos: CBC + Total testosterone
    • Erythrocytosis (gender marker in male range)
    • TT: 200-800; ask when last shot was (peak/trough); know your lab’s reference ranges for cis-men
  • Labs as needed /per USPSTF guidelines
    • Estradiol (want < 50)
    • LFTs → watch for gender marker
    • Lipids
    • Blood glucose
    • BP
    • CV RFs
18
Q

Estrogen Therapy Timeline
Irreversible Changes
for M > W

A
  • Sperm + semen production decrease
  • Testicles shrink
  • Breasts grow
19
Q

Estrogen Therapy Timeline
Reversible Changes

A
  • Body fat redistributes
  • Muscle mass decreases
  • Skin becomes softer
  • Libido/erections decrease
  • Body/facial hair becomes finer
  • Head hair loss slows
20
Q

Estrogen/Anti-androgen therapy risks

A
  • Estrogen used in tx less likely to cause clots vs. estradiol
  • GI : liver inflammation
  • CV : HTN, MI, stroke, Venous thromboembolism
  • Endocrine : Hyperprolactinemia
  • Renal : Electrolyte imbalances (spironolactone)
  • Reproductive : Infertility
21
Q

Pts w/CV risks - nonmed and med options?

A
  • Counsel pts about lifestyle modfications to lower risk, especially if they smoke or have FMHx of CVD
  • Trasndermal E for pts w/higher VTE + CVD risk
  • Baby aspirin for pts > 40 w/CV RF if smoking
22
Q

Estrogen Therapy: Dosage forms + adjuvant meds

A
  • INJ (estradiol valerate)
  • Topical - (safest form for ppl w/existing clot risk)
  • PO/ SBL (avoids 1st-pass effect → effective dosage)
    • Dvided dosing recommended if > 2mg
  • Other: Spironolactone (anti-androgen); Finasteride for hair loss, Cialis or Viagra
23
Q

Estrogen/Anti-androgen Therapy Monitoring

A
  • At baseline, at 3, 6, and 12 mos, then yearly:
    • BUN/Cr/K+ (spironolactone)
  • 3, 6, and 12 mos, then PRN:
    • Estradiol (100-300) + Testosterone levels
    • Total Testosterone: < 40 - don’t want 0 - lack o energy at 0
  • PRN per USPSTF guidelines
    • LFTs, Lipids, BG, BP, CV RFs, Prolactin
24
Q

ACHEs stand for?

Blood clots

A

Abd pain
Chest pain
HA
Eye problems (vision changes)
Severe leg pain
+ Prolactinoma (visual changes, HA, galatorrhea)

25
Q

Fertility considerations for Testosterone therapy

A
  • Ovulation usually difficult, but not impossible to get pregnant
  • Use Depo, IUD, POPs, Nexplanon, barrier methods
  • Consider egg harvesting + storage; freezing embryos

Bottom line: Testosterone is not birth control, but might make it impossible to conceive a child

26
Q

Fertility considerations for Estrogen/Anti-androgen Therapy

A
  • Sperm count + motility decrease, BUT it’s difficult, not impossible, to get someone pregnant
  • Consider banking sperm (better before hormone initiation), freezing embryos

Bottom line: estrogen is not birth control, but might make it impossible to conceive a child

27
Q

Fertility visit follow-up frequency for patients taking hormone therapy

A

Every few months in 1st year
Then yearly
- More frequently with dose changes

28
Q

Pap test considerations for transmasculine patients
What to use?

A
  • Unsatisfactory paps more common d/t long time on T
  • If unsastifactory test, need repeat in 2-4 mos
  • HPV testing too
  • Topical estrogen for repeat unsatisfactory Paps
  • Consider self-colelction of vaginal swab for HPV if Pap removed
  • T can make vagina atrophic + alter interpretation
29
Q

Genital bleeding considerations for transmasculine patients

A
  • Should stop after 3-6 mos on T
  • T too low? → breakthrough bleeding
  • T too high? → Aromatizing estrogen
30
Q

Chest exams for transmasculine patients

A
  • If no top surgery → cis women guidelines
  • If s/p top surgery → clinical chest wall exam + pt education
    • Not all breast tissue is removed
31
Q

HIV prophylaxis for transmasculine pts?

A

PrEP

32
Q

Mammogram considerations for transfeminine patients

A
  • Recommended after age 50 if following present:
    • Estrogen therapy for 5yrs ≤
    • FMHx of breast cancer
    • BMI > 35
33
Q

Prostate exams + PSA testing for transfeminine patients?

A

YES - even after bottom surgery, prostate remains

34
Q

Pap tests needed after bottom surgery?

Transfeminine

A

No - b/c no cervix