Levels of Chromosome Packing Flashcards
1
Q
Nucleosome
A
146 bp strand of DNA wrapped around 8 histone proteins
10 nm diameter = chromatin fiber
2
Q
146 bp
A
segment of DNA in a nucleosome
3
Q
Histones
A
8 in a nucleosome. histone families include H2A, H2B, H3, H4
4
Q
1.65 turns describes the number of turns
A
DNA is wrapped around histone
5
Q
___ bp of “linker” DNA associated with _____ extends from …..
A
54; H1; one core particle to the next
6
Q
Packing ratio with nucleosome structure
A
1:7
7
Q
Solenoid
A
formed by a tighter coiling of the chromatin fiber
30 nm diameter
packing ratio = 1.30
8
Q
additional packing
A
may occur through additional folding and coiling
packing ratio may reach an extreme of 1:10,000 during spermatogenesis
