Level 4 A&P Flashcards

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1
Q

What Pathology discipline processes samples for bacterial cultures that are taken at PM

A

Microbiology

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2
Q

What is DVT

A

(Deep vein thrombosis) results in pain, swelling, and tenderness in the affected area - usually in the leg

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3
Q

What can a DVT cause

A

DVT’s require urgent treatment as the blood clot can break off and make it to the lung. Where it can cause a PE (Pulmonary embolism)

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4
Q

What is a PE

A

Pulmonary Embolision- when a blood clot blocks a vessel in the lungs

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5
Q

Pneumonia affects which Organ?

A

The Lungs

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6
Q

What is Pneumonia? what is it usually caused by?

A

An inflammatory condition of the lung- affecting primarily the samll air sacs known as alveoli. It is usually caused by infection with viruses or bacteria

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7
Q

What are three major risk factors of developing gangrene?

A
  1. Diabetes
  2. Alcholism
  3. Smoking
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8
Q

What is Gangrene?

A

Gangrene is a condition where loss of blood supply causes body tissue to die. Typically starts in the toes, feet, fingers and hands.

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9
Q

How can you develop Gangrene?

A

Gangrene can occur as a result of an injury, infection, or a long term condition that affects blood circulation

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10
Q

Mesothelioma is linked to exposure of what?

A

Asbestos

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11
Q

What is mesothelioma?

A

A type of cancer that develops in the lining that covers the outer surface of some of the body’s organs. (Mainly affects the lining of the lungs)

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12
Q

At Post-Mortem examination what is a sign of Mesothelioma

A

Pleural Plaques

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13
Q

What pathology discipline processes samples for drug and Toxicology analysis that are taken at PM

A

Biochemistry

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14
Q

What is Biochemistry

A

Biochemistry is the study of chemical processes within and relating to living organisms.

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15
Q

In what organ does autolysis begin

A

The liver

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16
Q

What is Autolysis?

A

Self-digestion- where cell membranes breakdown and leak their contents l, this results in enzymes being released causing a rapid cascade of tissue breakdown.

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17
Q

True or False

Carbon monoxide is a poisonous gas that has a strong smell

A

False

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18
Q

What does carbon monoxide poison in a. persons bloodstream

A

The haemoglobin- this results in blood that can no longer carry blood round the body.

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19
Q

What is cyanosis?

A

A bluish colour in the skin, lips and nail beds.

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20
Q

What causes cyanosis

A

Cyanosis is caused by a shortage of oxygen in the blood.

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21
Q

In what circumstance will a person not present with cyanosis in spite of asphyxiation?

A

When a person has asphyxiated by carbon monoxide poisoning

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22
Q

What is Hazard Group 1’s definition.

A

Unlikely to cause human disease.

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23
Q

What is Hazard Group 2s definition?

A

Can cause human disease - unlikely to spread to the community, and there is usually effective treatment.

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24
Q

What Hazard Group 3’s definition?

A

Can cause severe human disease and may spread to the community- but there is usually effective treatment available

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25
Q

What is Hazard Group 4’s definition?

A

Causes severe human disease and is likely to spread to the community, and there is usually no effective treatment available.

26
Q

What type of PM should be carried out if a death is suspected to have occurred as a result of a crime

A

Forensic

27
Q

What is cachexia

A

Cachexia is a syndrome/condition where metabolic activity is altered, resulting in muscle, weight, and protein loss (Severe malnutrition). About 50% of cancer patients suffer from cachexia.

28
Q

What can cause an ischemic bowel

A

Reduced/blocked blood flow to the bowel.

29
Q

What is the process for histology

A

Sample is:
-Booked in
-Embedded in a cassette
-Processed in a tissue processor
-Cut on microtome
-Thin tissue slice added to slide
-Slide stained

30
Q

What causes creamy, purulent exudate on the surface of the brain?

A

Meningitis

31
Q

Muscle Hypertrophy involves an increase in muscle size through the growth in what?

A

The Size of the cells

32
Q

What can hypertension cause due to muscle hypertrophy

A

Ventricular Hypertrophy (Thickening of the Heart Walls)

33
Q

What is released from red blood cells when they are damaged?

A

Haemoglobin

34
Q

Is meningitis closely associated with septicemia

A

Yes

35
Q

What can meningitis cause?

A

life-threatening blood poisoning (septicemia)- resulting in damage to the brain or nerves.

36
Q

What is released when the heart is damaged either due to a blood clot or trauma.

A

Troponin

37
Q

When is molecular genetic testing of post mortem likely to break requested?

A

When the cause of death is due to an inherited condition.

38
Q

To send a PM tissue sample for genetic testing, how do you send it?

A

It must be sent fresh/frozen in a specimen pot and not in formalin

39
Q

What are diseases that cause caseous necrosis

A

TB, syphilis and fungi infections

40
Q

in what part of the body do microbes spread from following death

A

The intestines

41
Q

What is an infection if the inner surface of the heart called?

A

Infective endocarditis

42
Q

What can lead to infective endocarditis?

A

as heart valves do not have a dedicated blood supply. Any damaged valves can allow bacteria to grow on them, and that can lead to infective endocarditis

43
Q

A cancer that has spread from where it started to another part of the body is termed?

A

Metastatic

44
Q

A condition that is characterised by an excess of watery fluid collecting in the cavities or tissues of the body is called?

A

Oedema

45
Q

What does peripheral oedema affect?

A

The feet, ankles, legs, hands, and arms

46
Q

What is pulmonary oedema?

A

Excess fluid that has collected in the lungs that makes breathing difficult.

47
Q

What causes bilateral clubbing of the fingernails?

A

Malignant disease - Mostly of heart and lungs - However, it can occur for no obvious reason

48
Q

What is Marfan syndrome?

A

A genetic disorder of the body’s connective tissues

49
Q

What is the most serious sign/symptom associated with marfan syndrome?

A

Dilated aorta (can lead to thoracic aortic aneurysms).

50
Q

What is the pathology discipline for processing tissue samples for cell staining taken at PM

A

Histology

51
Q

Tissue taken at PM required to be sent for histology should be sent in what?

A

Formalin and a matching request form

52
Q

What are the different body types?

A

-The underweight body type
-The overweight body type
-The tall body type
-The yellow body
-The blue body
-The grey body

53
Q

What do you look at for a post-mortem external examination

A

-Body type
-Finger and toe nails
-Surgical scars and signs
-Limbs, Ulcers, Skin
- Trauma or hanging

54
Q

What is Jaundice caused by?

A

-Gallstone trapped in bile duct
-Pancreatic cancer
-liver if biliary malignancy
-Hepatitis

55
Q

what is an incision?

A

A clean-cut wound with a sharp object

56
Q

What is a laceration?

A

A wound produced by the tearing of body tissue, such as a blow from a blunt instrument.

57
Q

What is the difference between an embolism and a thrombus.

A

Thrombosis- Pure blood clot or thrombus forming in a vessel

Embolism- when a clot, fat or air bubble travels through the blood vessels with a risk of lodging somewhere else

58
Q

Where does an epidural haemorrhage (bleed) occur

A

Between the Skull and the dura mater

59
Q

Where does a subdural haemorrhage occur?

A

Between the dura and the arachnoid.

60
Q

what is hyperplasia

A

An increase in the number of cells

61
Q

What is Hypertrophy

A

An increase in the size of cells