Level 3 Flashcards
T score between -1.0 and -2.5
Osteopenia
Idiopathic avascular necrosis of the femoral head in a child; mild pain, limp, and Trendelenburg gait
Legg-Calve-Perthes disease
Most common cause of osteomalacia
Vitamin D deficiency
Osteoporosis is diagnosed with a DEXA T score below
-2.5
Subarachnoid hemorrhage is treated with which medication?
Nimodipine (calcium channel blocker)
Drug of choice for patients with subarachnoid hemorrhage and severely elevated BP
Labetalol
The blue-dot sign is pathognomonic for this condition
Torsion of the appendix testis (remnant of the paramesonephric duct)
Adult polycystic kidney disease is associated with
berry aneurysms, hepatic cysts, and thoracic aortic aneurysms
Goals of tx of hyperkalemia
1) Membrane stabilization (calcium chloride or gluconate)
2) Shift of K into cells (beta-agonist, IV sodium bicarb, or insulin + glucose)
3) Excretion (furosemide, sodium polystyrene sulfonate)
Charcot’s triad
Fever, Jaundice, RUQ pain
Reynold’s pentad
Fever, Jaundice, RUQ pain, AMS, hypotension
Patient presents with jaundice and pruritis, and is associated with Ulcerative Colitis
Primary Sclerosing Cholangitis
Inactivation of neutrophil elastase is associated with
alpha-1 antitrypsin deficiency
Primary ciliary dyskinesia and situs inversus
Kartagener syndrome
Most important and accurate test to make the diagnosis of acute pancreatitis
CT scan
Most common cause of acute pancreatitis
Gallstones
Presents as red, itchy, macerated plaques and erosions within the skin folds; a border of fine scale as well as satellitle papules and pustules
Candidal intertrigo
Most commonly presents with abdominal pain, neuropathy, and non-specific psych symptoms; no rash; Urine porphobilinogen and aminolevulinic acid will be elevated
Acute intermittent porphyria
Neuroendocrine tumor that typically arises in the midgut (appendix) and releases serotonin; flushing, abdominal pain, and diarrhea; urine levels of 5-hydroxyindoleacetic acid (5-HIAA) will be increased
Carcinoid tumor
Most common cause of postpartum hemorrhage
Uterine atony
Treatment of uterine atony starts with
uterine massage
Uterotonic drugs: oxytocin, carboprost, misopristol, and methylergonovine
Patients with pellagra commonly display
Dermatitis, Diarrhea, and Dementia (niacin deficiency)
The majority of renal calculi are
calcium stones
Used to treat ethylene glycol and methanol intoxication
Fomepizole (competitive inhibitor of alcohol dehydrogenase)
CHA2DS2-VASc
Congestive heat failure Hypertension Her (female sex) Age Diabetes Stroke (hx) Vascular disease (hx)
Blowing holosystolic murmur heard best at the left lower sternal border that increases with inspiration
Tricuspid regurgitation
Most common benign tumor in women
Leiomyomas
A process in which a left to right cardiac shunt reverses to a right to left shunt due to pulmonary HTN
Eisenmenger syndrome (most commonly due to a large, VSD or ASD)
Most common infection causing aplastic crisis in patients with sickle cell disease
Parvovirus B19
Renal biopsy shows IgG and C3 deposits as the basement membrane, with a “spike-and-dome” appearance
Membranous Glomerulonephritis
Erb-Duchenne’s palsy is caused by injury to which nerve roots?
C5-C6 (most common)
Klumpke’s palsy is caused by injury to which nerve roots?
C8-T1
Treatment of choice for central diabetes insipidus
Desmopressin
Best initial test for acromegaly
Insulin-like growth factor (IGF)
First lab to be increased after the induction of warfarin
PT/INR
Treatment of choice for H pylori
Amoxicillin, clarithromycin, and a PPI
Medications commonly implicated in drug-induced Lupus
Hydralazine, isoniazid, procainamide, penicilliamine
Caused by injury to C8-T1 nerve root causing Horner’s syndrome, ulnar nerve distribution numbness, and paralysis of the intrinsic muscles of the hand
Klumpke’s Paralysis
Most sensitive test for ruling out drug-induced lupus erythematosus
Anti-histone antibodies
Anti-thyroid-stimulating hormone (TSH) receptor antibodies are diagnostic of this condition
Graves disease
Anti-thyroid peroxidase (TPO) antibodies or anti-thyroglobulin antibodies are diagnostic of this condition
Hashimoto thyroiditis
Patient wants treatment for depression but low risk of sexual side effects
Bupropion
Atypical antidepressant that is contraindicated in patients with eating disorders
Bupropion
The Five W’s of post-op fever
Wind (atelectasis) Water (UTI) Wound (Infection) Walking (DVT) Wonder drugs (Med reaction)
Pinworm; can cause symptoms of appendicitis; associated with nocturnal pruritus ani (anal itching)
Enterobius vermicularis
Muscle shortens
Concentric
Muscle lengthens
Eccentric
The most specific tests for SLE
anti-Smith Ab and anti-dsDNA
Most sensitive test for ruling out SLE
antinuclear antibody (ANA)
First-line tx for Alzheimer’s
Donepezil, rivastigmine, or galantamine
Primitive neuroectodermal tumor most often arising in the diaphysis of extremity long bones in male patients; small round blue cells with hyperchromatic nuclei and minimal clear cytoplasm
Ewing sarcoma
Lymph nodes that drain the ovaries and testes
Para-aortic lymph nodes
Port wine stain of the face and seizures
Sturge-Weber (look for homonymous hemianopia)
Autosomal dominant disorder that is characterized by the combination of medullary thyroid carcinoma, primary hyperparathyroidism, and pheochromocytoma
MEN 2A Sipple Syndrome
Treatment of thyroid storm is with
PTU or methimazole
Patients should be evaluated __________ weeks after initiating treatment with levothyroxine
4-6 weeks
What is the diagnostic method of choice for lesions suspicious for malignant melanoma?
Excisional biopsy
The prognosis for malignant melanoma is related to
the depth of invasion (Breslow thickness)
Sinusoidal heart rate pattern on fetal tracing indicates
severe fetal anemia, usually due to Rh isoimmunization or severe hypoxia
Late decelerations are caused by
uteroplacental insufficiency
Umbilical cord compression causes
variable decelerations
Pressure of the fetal head causes
early decelerations
Most specific tests for RA
anti-CCP antibodies and radiographic findings
Infectious epididymitis in patients under 35 is most often caused by
Chlamydia trachomatis and Neisseria gonorrhoeae
Most common cause of infectious epididymitis in patients of 35 y/o
E. coli
Most likely breast cancer to be missed on mammography, even with a palpable lesion
Invasive lobular carcinoma
Most common type of breast cancer
Invasive ductal carcinoma
Most common cause of bloody nipple discharge
Intraductal papilloma
Most common type of testicular germ cell tumors and malignancy in patients between 15-35 y/o
Seminoma (“fried-egg appearance”)
Most common testicular cancer in prepubescent males; always presents with significantly elevated AFP levels
Yolk sac (endodermal sinus) tumor; may reveals Schiller-Duvall bodies
Which types of HPV causes the majority of genital warts?
6&11
Which types of HPV causes the majority of cervical cancers?
16&18
First-line pharmacological treatment for OCD
SSRI
Drug of choice for essential tremor
Propranolol
Fat embolism is associated with a(n)
petechial rash
The therapy of choice for TTP is
plasma exchange (FAT RN) Fever, Anemia, Thrombocytopenia, Renal disease, Neuro dysfunction
ADAMTS13 deficiency
Most common fungal cause of otitis externa
Aspergillus niger
Most common risk factor for dementia
Age
Most common cause of meningitis in adults?
S. pneumonia
Very common cause of meningitis in neonates
Group B Strep