LEVEL 1 CONDITIONS!!!! Flashcards
Neonatal jaundice
CAUSE?
when should it appear?
when is it pathological?
treatment?
complications?
tests:
- jaundice in neonate spreads head down
Cause: immature hepatocytes cant conjugate bilirubin -
breastfeeding prolongs this
appears on day 2-3 and peaks day 5
pathological within first 24 hours and should resolve within 10 days (preterm babies or breast fed 3/4 weeks)
Tx –> phototherapy and exchange transfusion.
IV ig if RH issue
complication: Acute bilirubin Encephalopathy or Kernicterus (histological deep yellow staining of brain tissue)
Tests: subcut bilirubin and serum bilirubin. if before 24 hrs, direct coombs for incompatibility.
if conjugated bilirubin +25% then post hepatic so refer to surgeon.
Immunisations Birth 8 weeks 12 weeks 16 weeks 1 year 3 year 4 months 2-8 years 12-13 M+F 14yrs
Birth –> Hrp B if mother infected and BcG to high risk (TB)
8 weeks –> Men B vaccine + Rotavirus gastroenteritis + pneumococcal + Infanrix Hexa (6) = Diptheria, tetanus, hepatitis B, polio, Haemo influenza B, pertussis whooping cough
12 weeks –> Infranix Hexa (6) + Rotavirus
16 weeks –> Infranix Hexa (6) + pneumoccal + MenB
1 year –> HiB + Men C = menitorax, + Pneumococcal, MMR + men B
3 year 4 months –> DTap/ IPV + MMR
2-8 years –> Influenza
12-13 M+F –> HPV 2 doses
14yrs –> Men A + Revaxis = (Tetanus, Diptheria and polio)
Meningitis
viral - most common cause?
bacterial- most common cause?
Presentation
ivx
treatment
changes in CSF
VIRAL - self limiting. most common: EBV, CMV, herpes, mumps, enterovirus
BACTERIAL-
Common cause neonate: group B strep, E.coli, listeria monocytogene
>6 yrs: strep pneumoniae, neiseria meningitides, haemo influenza
presentation:
Nuchal rigidity, Kernkigs + brundski sign
low threshold for infants as not classic syx
young: lethargy, poor feeding, non-blanching peuperic rash
older: neck stiffness, fever, headache,
ivx: LP to confirm diagnosis and identify organism. dont perform if raised ICP
Treatment:
1. <3months= Cefotxime + amoxicillin
2.over >3 months CEFTRIAXONE + vancomycin
Henoch Schonlein Purpura
Common in who?
Presentation + Tests
Management???
- Ig A mediated vasculitis from viral or bacterial infection in 2-11 years + boys
- RED-PURPLE NON BLANCHING RASH over legs and buttocks, skin swollen (Differentiate from meningitis with lack of neck stiffness)
- TRIAD of Arthritis, Colicky abdo pain and purpuric rash
- Moderate/severe –> rectal bleeding, arthralgia, deranged u+es
- IVX: bloods, culture, fbc, u+e, urine dip
- Tests: platelet count is normal unlike DIC
Test for nephritis as can have worse prognosis
- Most resolve within 6 weeks TX: 1. Paracetamol/ Nsaids for arthralgia 2. Corticosteroids for abdo pain and arthritis 3. Immunoglobulins
Severe –> Resus, steroids and renal review
Complications: kidney disease, orchitis, vasculitis, pulmonary haemorrhage, intusccuscetion
Septicaemia
CF
TX
Meningococcal Sepsis = most common cause of infectious death
CF: fever, SOB, Rigors, hypovol, widespread maculopapular rash becomes non-blanching
TX = IV BEN PEN + BUFALO
If meningitis
under 3 month s= cefotoxime
over 3 months =ceftriaxmine
Complications: DCI, aki, deafness, amputation
If cellulitis, penicillin
Prophylaxis close contacts given 2 days RIFAMPICIN
Iron deficiency anaemia
Treatment
MICROcytic HYPOchronic
Cause: infection, malabsorption, PICA, meckels,
Syx: pallor, lethargy, slow feeding, breathless
IVX: low MCV = lots of small RBC
low ferritin indicates low Fe stores
TFT to rule out hypothyroidism
Treatment = Ferritin 5mg/kg eg Sytron for 3 months
Screen for thalassaemia if no improvement
Asthma
IVX
Management
Reversible igE OBSTRUCTIVE
RF: atopic, FHX, obesity, premature, maternal smoking
Presentation; cough, worse at night, SOB, wheeze
LIFE THREATENING = 33, 92 chest + c02 normal
IVX: Spirometry if over 5 , FEV1/FVC less than 70%
Bronchiodilator reversibility 12% FEV = indicative
Management 1. SABA 2 + very low ICS (or LTRA if under 5) 3 + Very low ICS + LTRA (under 5) or LABA over 5 4 Increased to low ICS 5 specialist help
- Be careful with steroids for impaired growth, adrenal suppression, oral candidiasis
Bronchiolotis
Caused by?
IVX
When to admit?
management
vaccine to prevent?
Caused mainly by Respiratory Syncital Virus
Rare over 2 years
CF: Early –> coryxal, dry cough, mild fever, cold syx
CF: Late –> wheeze, poor feeding, apnoea, crackles, tracheal tug, hypoxia
IVX: nasopharyngeal swab fr RSV + CXR - show atelectasis and consolidation
Management:
- ADMIT IF <3 months, sats under 92&, Resp distress, apnoeas or dehydrated
Humidified 02 via nasal cannula Salbutamol over 12 months old CPAP if severe \+ PAVLIZUMAB monthly to RSV high risk groups Otitis media common
Croup
Age?
Cause?
PREsentation? Classic syx
management
6 months - 3 years
cause: Parainfluenza
Presentation: SUDDEN onset, seal like BARKING cough
Stridor, hoarse voice, resp distress
SEVERE = aggitation, lethargy
DDx = allergic reaction, Eppiglotits (drooling)
Management: do NOT examine throat
admit if RR >60
1. mild/mod = Dexamethasone
2. Severe = dex + Neb adrenaline + 02 therapy
Pneumonia
IVX
Management
older children
adolescent
Presentation: high grade fever, chest recessions, inc RR, cough, wheeze
IVX: CXr NOT routine
Nasopharangeal swab
Management: paracetemol, fluids, check had pneumococcal vaccine, nasal cannula if sats drop below 92%
TX: Amoxicillin older children
Erythromycin adolescents
or IV- co amoxiclav
URTI - tonsillitis and pharygntits
Centor criteria?
Can trigger what complications?
Centor criteria
- Score of 3+ give ABX
1. Fever
2. Absence of cough
3. Tonsillar exudate
4. anterior cervical lymphadenopathy
5. Temp <38
6. age 3-14
TX: antibiotics Penicillin or Erythromycin for 10 days
May get scarlet fever rash due to infection
Can preceed Acute Glomerulonephritis or acute rheumatic fever
Wheeze
Cause
treatment under 6 months and over
Common in young infants <2
Cause: atopic asthma, CF, congential lung abnormality, recurrent aspiration of feeds
Presentation: high pitched narrow airways
Low pitched wider airways
Monophonic = one obstruction
Polyphonic = multiple
Viral wheeze = no crackles and common <5 - child is completely well in between and presents similar to asthma
Treatment: >6 months Bronchodialtators eg salbutamol
Under 6 months Ipratropium
Avoid steroids
Cystic fibrosis
Presentation
IVX:
Management
When ABX?
Other treatments
Autosomal recessive - thickened mucus and secretions
Presentation: cough, wheeze, SOB, phlemg, meconium ileus, pancreatitis, diabetes, FTTm salty sweat
IVX: Guthrie/ heel prick test at 8 days old
Management: Physioherapy 2 X a day + postural mucus drainage
Annual Flu vaccine, bronchodialtor and mucolytics
Abx when child is well= FLUCLOXACILLIN
- IV when unwell and Oral Ciprofloxacin for chest infections
Lactulose to treat intenstinal obstructions
Nutrition = pancreatic supplements
Treat meconium ileus with enema
Constipation
Causes?
treatment for feacal impaction?
+ if not worked by 2 weeks?
Causes: Idiopathic, low fibre, hisrchprungs, hypothyroi, coaelic, sexual abuse
Children under 1 year = poor appetite that improves with passage, retentive posture (flexed back)
Children over 1 year = distress on passing stool
CF: anal pain on pooping, palpable abdo mass
Overflow diarrhoea
IVX: only if organic cause suspected eg TFT, coaelic screen
Management: Diet - increase fluids and fibre
Behavioural - toilet training
3 month treatment
1. Movicol 1st line (osmotic)
2. Lactulose (osmotic)
+ add oral stiumulant - Senna if movicol not working by 2 weeks
Gastroenteritis
Syx
Cause
IVX
Management
Key differentials
Syx: increase stool frequency +- vomiting, fever and abdo pain- watery diarrhoea
cause = Rotatvirus 50% cases or bacterial
IVX: stool cultures if suspect sepsis - blood mucus present?
Stool sample for C.diff toxin
Mangement: Vaccine against rotavirs 8 + 12 weeks
Oral rehydration therapy - syx resolve in 1 week
C.diff = Vancomycin + Metronidazole
Cholera - ampicillin
