Leukotriene receptor antagonist and synthesis inhibitors Flashcards
1
Q
Leukotriene receptor antagonist and synthesis inhibitors example
A
Montelukast - Antiasmatic
2
Q
Mechanism of action
A
- Binds cysteinyl leukotriene receptors
- Inhibit leukotrine on bronchial smooth muscles
3
Q
Major mediators of inflamation?
A
Cysteinyl leukotriene receptors
4
Q
Therapeutic effect
A
- bronchoconstriction
- vascular permeability
- mucosal edema
- mucus production
5
Q
Indications
A
- Prophylaxis, Chronic treatment for asthma
- relief of symptoms for seasonal allergic rhinitis
6
Q
A
