Leukotriene Receptor Antagonist

Question 1

Drugs in this class…(2)
(“-lukast)

Answer 1

-Zafirlukast
-Montelukast

Question 2

How do Leukotriene Receptor Antagonist work?

Answer 2

-Steroid that blocks receptors for the production of leukocytes
-Long onset(1-2 weeks)
-Long term management

Question 3

Why do we give Leukotriene Receptor Antagonist

Answer 3

-Long term treatment for asthma

Question 4

Absolute contradictions for Leukotriene Receptor Antagonist

Answer 4

-Allergy
-Acute asthma attacks

Question 5

Cautions for LRA

Answer 5

-Hepatic impairment

Question 6

DRUG/DRUG Interactions for LRA

Answer 6

-Several
-wafarin
-aspirin
-theophillin

Question 7

Adverse effects for LRA

Answer 7

-Flu-like symptoms
-Pharyngitis
-CNS effects
–>headache
–>dizziness
GI issues
–>nausea, vomiting, diarrhea, abdominal pain, elevated enzymes

Question 8

BLACK BOX WARNING

Answer 8

*AGGRESSIVE BEHAVIOR
* DEPRESSION & SUICIDE
*HALLUCINATIONS

Question 10

Implementations for LRA

Answer 10

-Monitor for infections
-Safety measures for adverse effects
-Patient teaching